Opaque DMT crystal

N,N-Dimethyltryptamine (or DMT for short) is a short acting psychedelic entheogen which allows a person's consciousness to voyage into the most incredible dimensions, visions, thoughts and experiences imaginable. It is most commonly classified as a psychedelic but also possesses some properties inherent to dissociatives. It is one of the most powerful yet mysterious psychedelics in existence, but in the opinion of many users, to classify DMT as merely a drug would be doing it a great injustice as DMT seems to some as a transdimensional key into places and vistas so profound and awe inspiring that it raises many new questions regarding the nature of reality and our place within it. Nevertheless, it is important to realize that the experience may be very difficult for some to integrate, and great care and respect is necessary to use it.

DMT exists naturally in every human being and also throughout the plant and animal kingdoms. It occurs naturally in many mammals, marine animals, trees, grasses, flowers and shoots.

Plants Containing DMT

(from Block 1994*; Smith 1977; Montgomery, pers. comm.; Ott 1993*; Schultes and Hofman 1980, 155*; supplemented)

Species Demonstrated Tryptamines
AGARICACEAE (FuNGI)  
Amanita citrina Gray DMT,5-MeO-DMT
Amanita porphyria (Fries) Secretan 5-MeO-DMT
Amanita spp. DMT, bufotenine
AIZOACEAE/MESEMBRYANTHEMACEAE  
Delosperma sp. DMT,MMT
Mesembryanthemum spp. DMT (?)
GRAMINEAE (POACEAE)  
Arundo donax 1. DMT, bufotenine, and others
Phalaris arundinacea 1. DMT, bufotenine, and others
Phalaris tuberosa 1. DMT, bufotenine, and others
Phragmites australis (Cav.) Trin. ex Steud. DMT
LAURACEAE  
Umbellularia californica (Hook. et A.) Nutt. 5-MeO-DMT
LEGUMINOSAE  
Acacia confusa Merr. DMT
Acacia maidenii F. von Mue1!. DMT (0.360/0)
Acacia nubica Benth. DMT
Acacia phlebophylla F. von Mue1!. 0.30/0 DMT
Acacia simpIicifolia Druce 0.810/0 DMT
Acaciaspp. DMT
Anadenanthera colubrina (VeIl.) Bren. DMT, 5-MeO-DMT, bufotenine
Anadenanthera peregrina (1.) Spag. DMT, 5-MeO-DMT, bufotenine
Desmanthus illinoensis (Michx.) MacMillan DMT (to 0.340/0)
Desmodium adscendens (Sw.) DC. var. adscendens DMT (?)
Desmodium caudatum DC. DMT
Desmodium gangeticum DC. DMT, bufotenine, and others
Desmodium gyrans DC. DMT, bufotenine, and others
Desmodium pulchellum Benth. ex Bak. DMT, bufotenine, and others
Desmodium racemosum Thunb. 5-MeO-DMT
Desmodium tiliaefolium G. Don DMT, bufotenine, and others
Desmodium triflorum DC. DMT, bufotenine, and others
Lespedeza bicolor Turcz. DMT, 5-MeO-DMT
Lespedeza bicolor var. japonica Nakai DMT,5-MeO-DMT
Lespedeza capitata Michx. DMT
Mimosa scabrella Benth. DMT
Mimosa tenuiflora (Willd.) Pair. [syn. Mimosa hostilis 0.570/0 DMT
Benth., Mimosa nigra]  
Mimosa verrucosa DMT
Mimosaspp. DMT and others
Mucuna pruriens DC. DMT, 5-MeO-DMT, bufotenine
Mucunaspp. DMT and others
Petalostylis cassioides Pritze1 DMT, tetrahydroharmane
Petalostylis labicheoides R. Brown DMT, tryptamine
Phyllodium pulchellum (1.) Desv. DMT
MALPIGHIACEAE  
Banisteriopsis argentea Spring. [syn. B. muricata (Cav.) Cuatr.] DMT, DMT
Diplopterys cabrerana (Cuatr.) Gates DMT,5
[syn. Banisteriopsis rusbyana]  
MYRISTICACEAE  
Iryanthera ulei Warb. 5-MeO-DMT
Osteophloeum platyspermum (DC.) Warb. DMT,5-MeO-DMT
Viroia calophylla Warb. DMT,5-MeO-DMT
Virola calophylloidea Markgr. DMT,5-MeO-DMT
Virola carinata (Spruce ex Benth.) Warb. DMT,5-MeO-DMT
Virola divergens Ducke DMT
Virola elongata (Spruce ex Benth.) Warb. DMT, 5-MeO-DMT
Virola melinonii (Benoist) A.C. Smith DMT,5-MeO-DMT
Virola multinerva Ducke DMT,5-MeO-DMT
Virola pavonis (DC.) A.C. Smith DMT
Virola peruviana (DC.) Warb. DMT,5-MeO-DMT
Virola rufula (DC.) Warb. DMT,5-MeO-DMT
Virola sebifera Aubi. DMT
Virola theiodora (Spruce ex Benth.) Warb. DMT,5-MeO-DMT
Virola venosa (Benth.) Warb. DMT, 5-MeO-DMT, and others
Virolaspp.  
OCHNACEAE  
Testulea gabonensis Pellegr. DMT
POLYGONACEAE  
Eriogonum sp. DMT
RUBIACEAE  
Psychotria carthaginensis Jacq. DMT
Psychotria poeppigiana Mueli. Arg. DMT
Psychotria viridis Ruiz et Pay. [syn. P. psychotriaefolia Stand!.] DMT
RUTACEAE  
Dictyoloma incanescens DC. 5-MeO-DMT
Dutaillyea drupacea (Baill.) Hartley 5-MeO-DMT
Dutaillyea oreophila (Baill.) Sevenet-Pusset 5-MeO-DMT
Evodia rutaecarpa Benth. 5-MeO-DMT
Limonia acidissima 1. DMT traces
Melicope leptococca (Baill.) Guill. 0.21% DMT
Pilocarpus organensis Rizzini et Occhioni 5-MeO-DMT
Vepris ampody H. Perro DMT
Zanthoxylum arborescens Rose DMT traces
Zanthoxylum procerum Donn. Sm. DMT

Dosage

Oral

DMT is rapidly metabolized by MAOMonoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). and should therefore be combined with a MAOMonoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin).-inhibitor such as Harmine when taken orallyRoute of administration in which the subject swallows a substance.. Otherwise, the effects will be underwhelming or barely noticeable.

Dosages for DMT, considering MAOs are fully inhibited, vary wildly depending on person, probably due to metabolism in great part. They can go from 30 to 150mg! If its your first time, start on the lower end!

Another factor is whether one is ingesting a whole plant brew or purified extracts. Often in ayahuasca analysis the amount of DMT found is very small (20-30mg), but also often there is redosing in ayahuasca sessions, but also its possible trace amounts of beta-carbolines and other alkaloids can improve MAOMonoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). inhibition, or that other inactive plant substances can help protect DMT from fast breakdown by any potential MAOMonoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). activity.

There are a few different ways to ingest it orallyRoute of administration in which the subject swallows a substance.:

  • Dissolved in acidic juice.
  • Rolled inside a bit of smoking paper and swallowed like a pill.
  • Put into 00 Capsules.
Oral
Light 30-50mg of DMT & 50-75mg Harmala alkaloids
Common 50-75mg of DMT & 75-100mg Harmala alkaloids
Strong 100mg+ of DMT & 100-150mg Harmala alkaloids

Smoked-Vaporized

Dosage given assumes 100% effective vaporization method.

Smoked & Vapourised
Light 10-15mg
Common 15-25mg
Strong 25-40mg+

Extracted DMT freebase can be vaporized for very potent effects that last around 10-15 minutes. DMT is ideally vaporized, as opposed to smoked. Vaporization is achieved by a controlled temperature that does not burn/combust DMT material (and potential impurities), but instead just makes DMT evaporate and be inhaled.

Vaporization is much smoother than smoking. Smoking leads to break down of DMT (and impurity) molecules into potential toxic nitrogen oxides, so not only it is harsher but also there is a significant loss of actives.

Vaporizing can be achieved with improvised vaporizers such as "The Inspirator mk II","The Machine" (both DIY) or commercially sold vaporizing pipes such as the Vapor Genie.

Insufflated

Insufflated doses vary wildly, start low. Dosages given are for freebase DMT, dosage for salt form may be a little bit higher.

Insufflated
Light 10-25mg
Common 25-50mg
Strong 50-125mg+

Insufflation of DMT is a less popular method of administration because it can cause extreme physical discomfort. DMT can be snorted in both freebase and salt forms. The most common salt utilized for insufflation is DMT Fumarate. Note that highly basic substances can damage the nasal passageway so the potential user is advised to proceed with caution. Preparations to make DMT insuflation more tolerable from DMT-Nexus

Intravenous

Intravenous DMT comes on extremely fast and is the most efficient method of use. The effects are extremely similar to vaporized DMT, though IV administration is much more dangerous. It is advised that potential users avoid intravenous administration of DMT and stick to vaporization.

Intravenous
Light 10-15mg
Common 15-25mg
Strong 25-40mg+

Duration

Oral
Onset 10-60 minutes
Total 4-8 hours
After-effects 2-3 hours

Smoked & Vapourised

Onset 0-3 minutes
Peak 10-15 minutes
Total 15-30 minutes

Insufflated

Onset 1-5 minutes
Total 45-60 minutes

Intravenous

Onset >1 minute
Total 30-45 minutes

Effects

Positive

  • Euphoria
  • Feeling of awe
  • Realizations about one's life

Neutral

  • Time dilation
  • Intense hallucinations
  • Dissociation
  • Loss of comprehension of basic concepts such as ego, language or one's own body.
  • Out-of-body experiences
  • Unconventional thought patterns

Negative

  • Panic attack/Bad trip
  • (oral only) Nausea/Vomitting

After effects

  • A lasting perspective shift is likely to occur.
  • Depersonalization/Derealization can occur after an experience and may last up to several months.
  • Some people experience long-term anxiety after an experience while others report a decrease in overall anxiety.

Harm Reduction

If ingesting DMT orallyRoute of administration in which the subject swallows a substance. with a MAOIMonoamine oxidase inhibitor are drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate., ensure that care is taken with the diet such that no food which may cause an interaction is ingested - as this is potentially deadly. Check Erowid's MAOI Foods To Avoid page for more information. However, if using a reversible MAOIMonoamine oxidase inhibitor are drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate. such as Syrian Rue, less care needs to be taken.

Refer to Psychedelic Harm Reduction for general information on psychedelic safety.

Images

Chemistry and Pharmacology

DMT is closely related to serotoninA monoamine neurotransmitter, biochemically derived from tryptophan, that is primarily found in the gastrointestinal (GI) tract, platelets, and central nervous system (CNS) of humans and animals. It is a well-known contributor to feelings of well-being., the naturally occurring neurotransmitter that psychedelics affect so widely. The pharmacology of DMT is similar to that of other well-known psychedelics. It affects receptor sites for serotoninA monoamine neurotransmitter, biochemically derived from tryptophan, that is primarily found in the gastrointestinal (GI) tract, platelets, and central nervous system (CNS) of humans and animals. It is a well-known contributor to feelings of well-being. in much the same way that LSD, psilocybin, and mescaline do. These serotoninA monoamine neurotransmitter, biochemically derived from tryptophan, that is primarily found in the gastrointestinal (GI) tract, platelets, and central nervous system (CNS) of humans and animals. It is a well-known contributor to feelings of well-being. receptors are widespread throughout the body and can be found in blood vessels, tissues, muscle, glands, and skin.


Production

There are a number of ways to acquire this entheogen. The first and most difficult way is to have some substantial chemistry knowledge and experience and actually synthesize pure DMT in a laboratory. This a rather tricky and time consuming process and requires access to some rather obscure and hard to acquire chemicals. The most common and easiest method to acquire DMT is to extract it from the various plant species that contain the compound. DMT occurs naturally in several plants and may therefore be extracted from them with little chemistry knowledge, requiring no actual synthesis.

Plants containing DMT include Mimosa hostilis/tenuflora, Psychotria viridis, Codariocalyx motorius, Diplopterys cabrerana, Acacia species, and Phalaris species.

Extraction Teks

Legal status

Europe

DMT is a class A substance in most European countries.

America

DMT is a schedule I substance in the United States.

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