DMT

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Opaque DMT crystal


General Information

N,N-Dimethyltryptamine or DMT for short is an short acting psychedelic entheogen which allows a person's consciousness to voyage into the most incredible dimensions, visions, thoughts and experiences imaginable. It is most commonly classified as a psychedelic but also possesses some properties inherent to dissociatives. It is one of the most powerful yet mysterious psychedelics in existence, but in the opinion of many users, to classify DMT as merely a drug would be doing it a great injustice as DMT seems to some as a transdimensional key into places and vistas so profound and awe inspiring that it raises many new questions regarding the nature of reality and our place within it. Nevertheless, it is important to realize that the experience may be very difficult for some to integrate, and great care and respect is necessary to use it.

DMT exists naturally in every human being and also throughout the plant and animal kingdoms. It occurs naturally in many mammals, marine animals, trees, grasses, flowers and shoots.

Dosage

Oral

DMT is rapidly metabolized by MAO and should therefore be combined with a MAO-inhibitor such as Harmine when taken orally. Otherwise, the effects will be underwhelming or barely noticeable.

Dosages for DMT, considering MAOs are fully inhibited, vary wildly depending on person, probably due to metabolism in great part. They can go from 30 to 150mg! If its your first time, start on the lower end!

Another factor is whether one is ingesting a whole plant brew or purified extracts. Often in ayahuasca analysis the amount of DMT found is very small (20-30mg), but also often there is redosing in ayahuasca sessions, but also its possible trace amounts of beta-carbolines and other alkaloids can improve MAO inhibition, or that other inactive plant substances can help protect DMT from fast breakdown by any potential MAO activity.

There are a few different ways to ingest it orally:

  • Dissolved in acidic juice.
  • Rolled inside a bit of smoking paper and swallowed like a pill.
  • Put into 00 Capsules.


Light: 30-50 mg of DMT and 50-75 mg Harmala alkaloids

Common: 50-75 mg DMT and 75-100 mg Harmala alkaloids

Strong: 100+ mg of DMT, 100-150+ mg of Harmala alkaloids

Smoked-Vaporized

Dosage given assumes 100% effective vaporization method.

Light: 10-15 mg

Common: 15-25 mg

Strong: 25-40+ mg

Extracted DMT freebase can be vaporized for very potent effects that last around 10-15 minutes. DMT is ideally vaporized, as opposed to smoked. Vaporization is achieved by a controlled temperature that does not burn/combust DMT material (and potential impurities), but instead just makes DMT evaporate and be inhaled.

Vaporization is much smoother than smoking. Smoking leads to break down of DMT (and impurity) molecules into potential toxic nitrogen oxides, so not only it is harsher but also there is a significant loss of actives.

Vaporizing can be achieved with improvised vaporizers such as "The Inspirator mk II","The Machine" (both DIY) or commercially sold vaporizing pipes such as the Vapor Genie.

Insufflated

Insufflated doses vary wildly, start low. Dosages given are for freebase DMT, dosage for salt form may be a little bit higher.

Light: 10-25 mg

Common: 25-50 mg

Strong: 50-125 mg

Insufflation of DMT is a less popular method of administration because it can cause extreme physical discomfort. DMT can be snorted in both freebase and salt forms. The most common salt utilized for insufflation is DMT Fumarate. Note that highly basic substances can damage the nasal passageway so the potential user is advised to proceed with caution. Preparations to make DMT insuflation more tolerable from DMT-Nexus

Injected

Intravenous DMT comes on extremely fast and is the most efficient method of use. The effects are extremely similar to vaporized DMT, though IV administration is much more dangerous. It is advised that potential users avoid intravenous administration of DMT and stick to vaporization.

Light: 10-15 mg

Common: 15-25 mg

Strong: 25-40+ mg

Duration

Oral

Onset: Between 10 and 60 minutes, depending on prior food intake.

Total: 3-8 hours until peak effects subside, several more until baseline is restored.

Smoked-Vaporized

Onset: A few seconds to a couple minutes.

Peak: 10-15min

Total: 15-30min

Insufflated

Onset: 1-5 minutes

Total: 45-60 minutes

Injected

Onset: Under 1 minute

Total: 30-45 minutes

Effects

Positive

  • Euphoria
  • Feeling of awe
  • Realizations about one's life

Neutral

  • Time dilation
  • Intense hallucinations
  • Dissociation
  • Loss of comprehension of basic concepts such as ego, language or one's own body.
  • Out-of-body experiences
  • Unconventional thought patterns

Negative

  • Panic attack/Bad trip
  • (oral only) Nausea/Vomitting

After effects

  • A lasting perspective shift is likely to occur.
  • Depersonalization/Derealization can occur after an experience and may last up to several months.
  • Some people experience long-term anxiety after an experience while others report a decrease in overall anxiety.

Harm Reduction

  • Operating machinery is definitely out of the question while under the influence.
  • Be careful for drugs or foods interacting dangerously with any MAO-inhibitors.
  • Only trip in a comfortable and positive environment.

Chemistry and Pharmacology

DMT is closely related to serotonin, the naturally occurring neurotransmitter that psychedelics affect so widely. The pharmacology of DMT is similar to that of other well-known psychedelics. It affects receptor sites for serotonin in much the same way that LSD, psilocybin, and mescaline do. These serotonin receptors are widespread throughout the body and can be found in blood vessels, tissues, muscle, glands, and skin.


Production

There are a number of ways to acquire this entheogen. The first and most difficult way is to have some substantial chemistry knowledge and experience and actually synthesize pure DMT in a laboratory. This a rather tricky and time consuming process and requires access to some rather obscure and hard to acquire chemicals. The most common and easiest method to acquire DMT is to extract it from the various plant species that contain the compound. DMT occurs naturally in several plants and may therefore be extracted from them with little chemistry knowledge, requiring no actual synthesis.

Plants containing DMT include Mimosa hostilis/tenuflora, Psychotria viridis, Codariocalyx motorius, Diplopterys cabrerana, Acacia species, and Phalaris species.

Extraction Teks

Images

DMT freebase molecule (N,N-DMT)

Legal status

Europe

DMT is a class A substance in most European countries.

America

DMT is a schedule I substance in the United States.