5-HTP
5-HTP
Dose Light Theraputic (anxiety): 50mg-100mg Common Theraputic (sleep): 100mg-200mg Recovery Dose (ie comedown of MDMA) 200-300mg (excess of 300mg
Duration 4-6 hours
Onset 30-60 minutes
Effects Mood Stabilization, Euphoria, sleep aid, antidepressant, appetite suppressant, possible nausea
Avoid Anything that interacts with serotonin levels or is serotonergic including SSRIs, MAOIs (in large doses), DXM, MDMA (during or before)
Aliases 5HTP 5-Hydroxytryptophan Tryptophan L-Tryptophan oxitriptan
Summary An amino acid that is the precursor to serotonin. 5-HTP is sold over the counter in the United Kingdom, the United States and Canada as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid. It is also useful in the recovery from certain psychedelics that drain serotonin such as MDMA (See ~drugs 5-HTP MDMA
Categories Mood stabilizer, Anti-depressant, recovery
Half Life The biological half-life of 5-HTP ranged from 2.2 to 7.4 hours, and the plasma clearance ranged from 0.10 to 0.23 1/kg/hour
After-Effects Minimal, slight depression/anxiety after repeated use
MDMA MDMA and 5-HTP are dangerous when done at the same time. However, 5-HTP can mean a world of difference for recovering from MDMA and other drugs.
One must use 5-HTP AFTER your MDMA high fades and the dysphoric comdown begins. Wait AT LEAST 5-6 hours after the last dose of MDMA.
The basis for doing this is that 5-HTP is a necessary precursor for the brain to produce more serotonin, and MDMA use depletes a person's natural serotonin levels, thus taking 5-HTP after consuming MDMA is speculated as helping improve serotonin production.