Quick Guide to Uncommon Stimulants
2-MDP - Dissociative anaesthetic, NMDA antagonist, simlar effects to PCP in animals, (-) isomer is active. Roughly 1/3rd potency of amphetamine by weight. Lasts over 24 hours.
2C-B-BZP - Benzylpiperazine base with ring-sub pattern of 2c-b. Not a phenethylamine, doesn't produce psychedelic effects. Lasts 3-6 hours. Was sold in Japan in "smartshops"
A-366/833 - Agonist at neural nicotinic acetylcholine receptors selective for α4β2 subtype. Been researched as an analgesic. Hasn't passed clinical trials.
A-84/543 ^ That and is used as the "standard" for this family of compounds.
2-Acetoxycocaine - Quicker onset than Cocaine. Four fold increase over cocaine in binding potency for dopamine. And 35 fold enhanced affinity for the norepinephrine. Reduced selectivity for serotonin. Interesting structure.
Adrafinil - Prodrug of Modafinil, unregulated in the US. 1 hour half life.
AL-1095 - Centrally acting, comparable efffects to amp. developed by Bristol in the 70's.
Altinicline (SIB-1508Y) agonist at neural nicotinic acetylcholine receptors similar to A-366. Releases Dopamine and Acetylcholine in both rodent and primate models. Progressed into Phase 2 clinical trials for Parkinson's.
Amfepramone - Diethylcathinone. By itself lacks any affinity for monoamine transporters and functions as a prodrug to ethcathinone. Very weak dopaminergic and serotonergic. 10-20x stronger on norepinephrine in comparison. Basically can be considered NRA's. Is currently Schedule IV in the United States. Class C drug in the UK. Apparently known as "tombstones" in the UK.
2-amino-1,2-dihydronaphthalene - Also known as 2-AD, rigid analogue of phenylisobutylamine and substitutes amphetamine for it in rat discrimination tests, 1/4th the potency. Closely related to 2-aminotetralin.
2-Aminoindane - 2-AI(RC) Psychoactive compound. Rigid analogue of amphetamine.
5-(2-aminopropyl)indole - 5-IT(RC) indole derivative. Preparation was first reported in 1962 by Albert Hofmann. Positional isomer of AMT. Closer chemically resembles
Phethylamines like 5-apb and the likes. Falls under the Analog act in the US with AMT.
6-(2-Aminopropyl)indole - ^. But it has been shown to increase hemoglobin levels in the bloodstream.
Aminorex - Known by many other names. Anorectic stimulant. Is classed within the 2-amino-5-aryl oxazoline class. Closely related to 4-methylaminorex. Shown to have locomotor stimulant effects, lying midway between dextro-amp and Meth. Attributed to the release of cathecholamines. Retired from the market after it was found to result in pulmonary hypertension.
2-Aminotetralin - (2-AT) consiting of a tetralin group combined with an anime. Rigid analogue of phenylisobutylamine. Fully substitutes for D-Amp in rat discrimination tests.
Although at 1/8th the potenct. Inhibits the reuptake of serotonin and norepinephrine. Likely induces their release as well. Also likely to act of Dopamine on account of the D-Amp.