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| == Dosage == | | == Dosage == |
| {| class="wikitable"
| |
| |+Comparison of benzodiazepines
| |
| ! Chemical name (brand name)
| |
| ! Half-Life [Active Metabolites]
| |
| ! Dose Equiv. of 10mg Diazepam (Oral)
| |
| ! Class
| |
| |-
| |
| | Alprazolam (Xanax)
| |
| | 6 - 12 hours
| |
| | 0.5 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Bromazepam (Lexotan, Lexomil)
| |
| | 10 - 20 hours
| |
| | 5 - 6 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Chlordazepoxide (Librium)
| |
| | 5 - 30 hours [36 - 200 hours]
| |
| | 25 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Clobazam (Frisium)
| |
| | 12 - 60 hours
| |
| | 20 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Clonazepam (Klonopin)
| |
| | 18 - 50 hours
| |
| | 0.5 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Clorazepate (Tranxene)
| |
| | [36 - 200 hours]
| |
| | 15 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Diazepam (Valium)
| |
| | 20 - 100 hours [36 - 200 hours]
| |
| | 10 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Estazolam (ProSom, Nuctalon)
| |
| | 10 - 24 hours
| |
| | 1 - 2 mg
| |
| | Hypnotic
| |
| |-
| |
| | Flunitrazepam (Rohypnol)
| |
| | 18 - 26 hours [36 - 200 hours]
| |
| | 1 mg
| |
| | Hypnotic
| |
| |-
| |
| | Flurazepam (Dalmane)
| |
| | [40 - 250 hours]
| |
| | 15 - 30 mg
| |
| | Hypnotic
| |
| |-
| |
| | Halazepam (Paxipam)
| |
| | [30 - 100 hours]
| |
| | 20 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Ketazolam (Paxipam)
| |
| | 30 - 100 hours [36 - 200 hours]
| |
| | 15 - 30 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Loprazolam (Dormonoct)
| |
| | 6 - 12 hours
| |
| | 1 - 2 mg
| |
| | Hypnotic
| |
| |-
| |
| | Lorazepam (Ativan)
| |
| | 10 - 20 hours
| |
| | 1 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Lormetazepam (Noctamid)
| |
| | 10 - 12 hours
| |
| | 1 - 2 mg
| |
| | Hypnotic
| |
| |-
| |
| | Medazepam (Nobrium)
| |
| | 36 - 200 hours
| |
| | 10 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Nitrazepam (Mogadon)
| |
| | 15 - 38 hours
| |
| | 10 mg
| |
| | Hypnotic
| |
| |-
| |
| | Nordazepam (Nordaz)
| |
| | 36 - 200 hours
| |
| | 10 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Oxazepam (Serax)
| |
| | 4 - 15 hours
| |
| | 20 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Prazepam (Centrax)
| |
| | [36 - 200 hours]
| |
| | 10 - 20 mg
| |
| | Anxiolytic
| |
| |-
| |
| | Quazepam (Doral)
| |
| | 25 - 100 hours
| |
| | 20 mg
| |
| | Hypnotic
| |
| |-
| |
| | Temazepam (Restoril)
| |
| | 8 - 22 hours
| |
| | 20 mg
| |
| | Hypnotic
| |
| |-
| |
| | Triazolam (Halcion)
| |
| | 2 hours
| |
| | 0.5 mg
| |
| | Hypnotic
| |
| |}
| |
|
| |
| {| class="wikitable"
| |
| |+Non-benzodiazepines commonly referred to as Z-drugs
| |
| ! Chemical name (brand name)
| |
| ! Half-Life [Active Metabolites]
| |
| ! Dose Equiv. of 10mg Diazepam (Oral)
| |
| ! Class
| |
| |-
| |
| | Zaleplon (Sonata)
| |
| | 2 hours
| |
| | 20 mg
| |
| | Hypnotic
| |
| |-
| |
| | Zolpidem (Ambien)
| |
| | 2 hours
| |
| | 20 mg
| |
| | Hypnotic
| |
| |-
| |
| | Zopiclone (Imovane)
| |
| | 5 - 6 hours
| |
| | 15 mg
| |
| | Hypnotic
| |
| |-
| |
| | Eszopiclone (Lunesta)
| |
| | 6 hours
| |
| | 3 mg
| |
| | Hypnotic
| |
| |}
| |
|
| |
|
| === Oral === | | === Oral === |
Revision as of 18:27, 4 March 2013
Classification: Downer/Sedative/Anxiolytic
History
Dosage
Oral
Onset:
Alprazolam IR : 8-25 minutes
Alprazolam XR : 25-75 minutes
Diazepam : Rapid
Clonazapam: 1 hour
Peak Benefit:
Diazepam: 1.6 hours
Alprazolam IR : 90 minutes
Alprazolam XR : 25-75 minutes
Diazepam : 2-4 hours
Clonazapam: 1-4 hours
Half/Life and Duration
Triazolam: 2.5 Hours
Lorazepam:
Alprazolam IR : 11 hour half life - 5 hour duration
Alprazolam XR :11-16 hour hour half life, 11 hour duration
Diazepam : 20-100 hour half life - 6-8 hour duration
Clonazepam: 18-50 hour half life - 12+ hours
Dosages Depend on tolerance.
Potentiators:
-Grapefruit juice
Avoid:
-Excessive drinking (you will die)
Smoked
Duration: X hours
Onset: X minutes
Low dose: X mg
Medium (typical) dose: X mg
High dose: X mg
Insufflated
NOT RECOMMENDED
Duration: X hours
Onset: X minutes
Low dose: X mg
Medium (typical) dose: X mg
High dose: X mg
Injected
NOT RECOMMENDED
Duration: X hours
Onset: X minutes
Low dose: X mg
Medium (typical) dose: X mg
High dose: X mg
Effects
Positive
- Stress Relief
- Anxiety Relief
- Social Anxiety
- PTSD
- Sedative
- Worries drift away
- That "sink into the couch" feeling
Neutral
Negative
- High addiction potential
- Killer withdrawals
- Risk of blackout
- Inability to drink
- Inability to dirve
- Loss of balance
- Memory Loss
- Procrastination
After effects
Harm Reduction
- Avoid driving and operating heavy machinery
- Recommended time (pauses) between using the substance
- Addiction potential - High
- Risk of death when mixed with alcohol
- CNS depressant when mixed with other drugs
Chemistry and Pharmacology
Production
Images
Legal
Europe
America
Asia
italic caption