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| | | [[Category:Drugs]] |
| <table style="font-family: Arial, Helvetica, sans-serif; font-size: 9pt;" width="100%" border="0" cellspacing="0" cellpadding="0">
| | [[Category:Stimulant]] |
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| <tr>
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| <td valign="top" width="50%"><strong>Other Names</strong>
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| Benzoylecgoninmethylester, cocain, cocaIn, cocaina,
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| d-cocain, erythroxylin, kokain, methylbenzoylecgonine,
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| methylbenzylekgonin, (±)-methyl- [3J3benzoyloxy-
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| 2a( 1aH,5aH)-tropancarboxylate], 0benzoyl-
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| [(- )-ekgonin] -methylester, 3-benzoyloxy8-
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| methyl-8-azabicyclo [3.2.1] octan-2-carboxylicacidmethylester,
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| 3J3 -benzoyloxy-2J3 -tropancarboxylicacid-
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| methylester
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| <strong>Street Names</strong>
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| Autobahn, blow, C, candy, charlie, coca, coca pura
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| (Spanish, "pure coca»), coco, coke, cousin, donuts,
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| doppelter espresso, flake, koks, la blanca, lady
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| snow, la rubiecita, line, linie, mama coca, nasenpuder,
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| nose candy, peach, perica, puro (Spanish,
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| "pure»), schnee, schneewittchen, schniefe, schnupfschnee,
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| sniff, snow, snowwhite, strasse, strasschen,
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| Ziggy's stardust
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| Empirical formula: C17H21N04
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| Substance type: coca alkaloid
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| The cocaine molecule is structurally related to
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| tropine and other tropane alkaloids (Roth and
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| Fenner 1988, 311*). Today, cocaine is the most
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| consumed psychoactive plant constituent in the
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| world. Pure cocaine (as a base) is not water soluble
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| but can be dissolved in alcohol, chloroform,
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| turpentine oil, olive oil, or acetone. Cocaine salts
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| are water soluble.
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| <strong>
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| History</strong>
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| In 1860, the German chemist Albert Niemann first
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| isolated cocaine from the leaves of the Peruvian
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| coca bush (Erythroxylum coca). The German
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| pharmacist Friedrich Gaedeke (1855) may have
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| represented the alkaloid before this. By around
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| 1870, cocaine was being used as an agent of
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| pleasure, and it was employed at this time to treat
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| alcohol and morphine withdrawal as well as
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| melancholy. The ophthalmologist Karl Koller, a
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| friend of Sigmund Freud, introduced cocaine as a
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| local anesthetic for eye surgery in 1884. Hermann
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| Goring's use of cocaine was famous, and Adolf
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| Hitler, who also used other stimulants (cf. strychnine),
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| is thought to have consumed cocaine as well
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| (Phillips and Wynne 1980, 112).
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| Later, other substances derived from cocaine,
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| including eucaine, procaine (= Novocaine), tetracaine
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| (= Pantocaine) (1930), lidocaine (= Xylocaine)
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| (1944), mepivacaine (= Scandicaine) (1957),
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| prilocain (= Xylonest) (1960), bupivacaine (1963),
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| and etidocain (= Duranest) (1972), were also used
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| as local anesthetics (Busch and Rummel 1990;
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| Schneider 1993, 19*). Holocaine was also regarded
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| as a substitute.
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| The goal of chemists and pharmacologists to
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| carve out the effective core of the cocaine
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| molecule and retain the desirable and remove
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| the undesirable effects was achieved in an
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| exemplary manner with the synthesis of procaine
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| (1905). (Busch and Rummel 1990, 490)
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| In 1923, Willstadter and his coworkers worked
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| out the complete synthesis of cocaine. The precursors
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| are succindialdehyde, methylamine, and
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| mono-methyl-J3-keto-glutarate. However, this synthesis
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| has never achieved pharmaceutical importance.
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| Practically speaking, all of the cocaine used
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| in the pharmaceutical industry is derived from the
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| coca plant. In 1976,410 kg of cocaine were legally
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| extracted for this purpose (Taschner and Richtberg
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| 1982,64).
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| <strong>Production and Use</strong>
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| An analysis of thirteen South American Erythroxylum
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| species found that cocaine is present only
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| in Erythroxylum coca and Erythroxylum novogranatense
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| (Holmstedt et al. 1977). Hair analysis of
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| Egyptian mummies has revealed the presence of
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| ecgonin, the first metabolite of cocaine, which indicates
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| that the ancient Egyptians either consumed
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| cocaine or an unknown African plant that metabolizes
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| to ecgonin (Balabanova et al. 1992*).
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| The coca plantations that are the source of
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| cocaine are known as cocales. Bolivian huanaco
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| leaves (Erythroxylum coca var. coca) are preferred for
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| cocaine production because they are the highest
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| yielding. With good chemicals and chemists, it is
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| possible to produce 1 kg of pure cocaine from 100
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| kg of coca leaves. In the early 1980s, some 100 tons
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| ofpure cocaine were exported from Colombia alone.
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| The entire process of cocaine production, as
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| well as the smuggling routes, the cartels, and everything
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| from the connections between politicians
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| and the cartels to the consumption of cocaine
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| even by politicians in the White House, has been
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| documented in countless reports on the radio and
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| television and in magazines and well-researched
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| books (Morales 1989). It is difficult to escape the
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| impression that the cocaine saga is one of the bestknown
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| stories of our times but one that is officially
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| ignored. Our leaders still act as though the
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| Mafia is using the white powder to corrupt and
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| dominate the world. In reality, the chief benefactors
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| of the billion-dollar business are the banks
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| and the countless politicians and law-enforcement
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| personnel involved in the trade (Sauloy and Le
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| Bonniec 1994).
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| The snuffing of crystallized cocaine appears to
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| have been discovered in North America at the
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| beginning of the twentieth century and spread
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| from there. Shortly after 1900, pure cocaine was
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| being ingested together with betel and lime in
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| India, Ceylon (Sri Lanka), and Java. The use of
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| cocaine as an athletic doping agent began in the
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| 1940s (Fiihner 1943, 195*). Little has changed
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| since that time. Cocaine dealers still find some of
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| their best customers in the soccer stars of the
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| German first league and sports heroes in the
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| United States.
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| Basuko is dried cocaine base (an intermediate
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| step in the production of the pure alkaloid).
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| Sucito, or joints made of basuko, have been
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| smoked in Colombia since about 1930 (Siegel
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| 1982b, 274). Cocaine is usually produced as a
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| hydrochloride but sometimes also as an oxalate or
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| hypochloride (HCL). Street cocaine is almost
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| exclusively cocaine HCL. Most of the illicit cocaine
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| available in Europe is only about 30% pure, as the
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| expensive pure drug is usually "cut:' The substances
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| that are most commonly used to "cut"
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| cocaine are:
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| • Inactive additives: milk sugar (lactose), grape
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| sugar (glucose), baking powder, talc (talcum),
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| borax, cornstarch, innositol, mannitol
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| • Active additives: speed (amphetamine, fenetyllin,
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| ritalin) and "freeze" (novocaine, benzocaine),
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| PCP ("angel dust"), methedrine,
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| pemoline, yohimbine, lidocaine, procaine,
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| tetracaine, caffeine, quinine, heroin (Taschner
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| and Richtberg 1982,65; Voigt 1982,84)
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| <strong>Dosage</strong>
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| A «line" of cocaine typically contains between 20
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| and 100 mg of cocaine, depending on the purity of
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| the substance and the consumer's preference.
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| Many users consume between 2 and 3 g in a day or
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| night. It is said that «the first line of the day is the
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| best."
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| <strong>Ritual Use</strong>
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| Cocaine has been called the champagne of drugs,
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| the drug of high society, the drug of the rich, et
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| cetera, and. it is certainly most often associated
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| with the wealthier classes. As a result, consumption
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| of the drug has taken on a strong social
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| character. Cocaine is rarely used by one person
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| alone. When it is taken with others, the consumption
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| follows a rather well-defined ritual. The person
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| providing the costly substance lays out several
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| lines (preferably on a mirror), then takes a
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| currency note (often of high value) and rolls it up.
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| One end of the rolled bill is placed in a nostril and
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| held with one hand, while the other hand is used
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| to press the other nostril closed. Half of one line,
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| or a small line, is then snuffed into the nostril. The
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| person then switches nostrils and snuffs the
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| remaining powder, after which the mirror is
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| passed to the next person. This circle may be
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| repeated several time, and it is customary for each
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| of several participants to prepare lines from their
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| own supply.
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| <strong>Artifacts</strong>
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| The cultural significance of cocaine in the modern
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| world cannot be overlooked. Artists, musicians,
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| and writers use it as a stimulant, while highly paid
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| computer experts, software engineers, and programmers
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| would hardly be able to keep up with
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| the demands of their jobs without their «coke."
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| Stockbrokers, financial gurus, and election staffers
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| may use cocaine until they are ready to collapse.
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| Even some of the soccer stars who jog into the
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| stadium sporting T-shirts with such incongruous
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| imprints as «Keine Macht den Drogen" C(No
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| Power to Drugs") are high as a kite on cocaine.
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| According to several estimates, the highest per
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| capita consumption of cocaine is found in Silicon
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| Valley and on Wall Street.
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| The first literary treatment of cocaine is found
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| in the Sherlock Holmes novel A Scandal in
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| Bohemia, by Sir Arthur Conan Doyle, published
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| only two years after Koller's discovery (Phillips
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| and Wynne 1980, 45). In this book, the astonishing
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| abilities of this brilliant detective are attributed in
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| part to his use of cocaine. By the time of the following
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| novel, The Sign of the Four, Sherlock
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| Holmes is injecting the pure alkaloid intravenously
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| (Voigt 1982,38).
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| The most famous novel of the British writer
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| Robert Louis Stevenson, Dr. Jekyll and Mr. Hyde,
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| was written in only four or six days and nightswith
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| the assistance of the magic powder, of course
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| (Springer 1989,8; Voigt 1982,38).
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| The novellas of the expressionist poet Walter
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| Rheiner (1895-1925), in which he referred to the
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| drug as «the eternal poison" and «the loved and
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| hated poison," played a great role in shaping the
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| image of demonic seduction by pharmaceutical
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| cocaine (Rheiner 1979).
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| At the beginning of the twentieth century, the
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| physician Gottfried Benn (1886-1956) wrote and
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| published numerous poems about cocaine (of
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| which he was very fond) that at the time were
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| deemed rather shocking (Benn 1982; vom Scheidt
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| 1981, 401). Many other authors have also been
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| inspired by cocaine, including Georg Trakl,
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| Thomas Zweifel, Josef Maria Frank Fritz von
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| Ostini, Klaus Mann, and Jean Cocteau (Springer
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| 1989).
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| Cocaine is also the subject of many novels. The
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| classic cocaine novel, Cocaine, was written by
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| Pitigrilli (= Dino Serge, 1927). The drug has often
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| been treated within its current criminal context
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| (Badekerl 1983; Fauser 1983), while other novels
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| have been written from a futuristic perspective (Boye 1986). The "coke scene" has also provided a
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| rich source of literary inspiration (McInerney
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| 1984; Ellis 1986).
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| The composer Richard Strauss (1864-1949)
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| wrote his opera Arabella while under the influence
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| of cocaine (Springer 1989,8; Timmerberg 1996).494
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| Countless compositions have had cocaine as their
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| subject, including Cocaine IiI, for a mezzosoprano
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| and four female jazz singers, by the
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| contemporary composer Nancy van de Vate (CD
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| Ensemble Belcanto, Koch, 1994). From the 1920s
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| to the 1940s, the white powder fueled the work of
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| especially jazz and blues musicians, and Chick
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| Webb, Luke Jordan, and Dick Justice even gave it a
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| musical treatment ("Cocaine Blues").
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| Veritable blizzards of cocaine have passed
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| through the brains of many of rock music's greats,
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| who then set their experiences with the "fuel" to
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| music. A few examples are Country Joe McDonald
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| ("Cocaine"), Black Sabbath ("Snowblind"), Little
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| Feat C'Sailin' Shoes"), the Rolling Stones ("Let It
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| Bleed"), Jackson Browne ("Cocaine"), and David
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| Bowie ("Ziggy Stardust").
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| The "hippie" band known as the Grateful Dead
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| sang about the white powder in their song
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| "Truckin'," one of their few hits to make it onto the
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| charts. Eric Clapton's interpretation of J. J. Cale's
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| song "Cocaine" became a worldwide success and
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| has been played millions of times over. The reggae
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| artist Dillinger released an album named Cocaine.
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| The drug also left its mark on the German music
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| scene, influencing or even appearing in the music
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| of Hannes Wader, Konstantin Wecker, Abi Ofarim,
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| and T'MA a.k.a. Falco ("Mutter, der Mann mit
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| dem Koks ist da" ["Mother, the Man with the Coke
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| Is Here"]; BMG Records 1995).
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| Cocaine has been the subject of at least one
| |
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| theater work: The American playwright Pendleton
| |
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| King wrote a piece entitled Cocaine that was
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| produced for the stage in 1917 (Phillips and
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| Wynne 1980,93 ff.).
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| <strong>Medicinal Use</strong>
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| The medicinal applications of cocaine were
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| discovered only a short time after the isolation of
| |
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| the molecule itself. Cocaine was initially used for
| |
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| local anesthesia495 in ophthalmology and dentistry,
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| and infiltration anesthesia was developed just
| |
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| a few years later (Custer 1898). Because analogs
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| (e.g., procaine) were developed that produce
| |
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| specific effects with no psychoactive side effects,
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| cocaine is rarely used as an anesthetic today.</td>
| |
| <td valign="top" width="53%"><strong>Pharmacology and Effects</strong>
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| Cocaine stimulates the central nervous system,
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| especially the autonomic (sympathetic) system,
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| where it inhibits the reuptake of the neurotransmitters
| |
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| noradrenaline, dopamine, and
| |
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| serotonin and increases the time in which they
| |
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| remain in the synaptic cleft. Cocaine has a powerful effect upon the peripheral nervous
| |
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| system, which explains its efficaciousness as a local
| |
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| anesthetic. It has strong stimulant and vasoconstricting
| |
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| properties. Very high dosages of cocaine
| |
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| are said to be able to induce hallucinations, an
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| effect that is frequently noted in the neurological
| |
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| literature (Pulvirenti and Koob 1996,49) as well as
| |
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| in prose and poetry (Rheiner 1979, 27).
| |
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| Hallucinations (of nonexistent people, images,
| |
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| flickering lights) often occur during nights in
| |
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| which dosages of 2 to 3 g have been taken. For
| |
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| many people, cocaine also dispels fear. It stimu1ates
| |
| | |
| a need for alcoholic beverages at the same
| |
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| time that it strongly suppresses the effects of
| |
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| alcohol. A similar dynamic applies to nicotine.
| |
| | |
| In a certain sense, there is something unsatisfying
| |
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| about the effects of cocaine. A person may
| |
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| sense that satisfaction could be achieved if the
| |
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| effects could possibly be increased. However, using
| |
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| more cocaine does not produce an enhancement
| |
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| of its effects.
| |
| | |
| Just as coca was and is employed in South
| |
| | |
| America as an aphrodisiac, cocaine has a similar
| |
| | |
| use in the West. Cocaine's reputation as an aphrodisiac
| |
| | |
| can be traced back to Sigmund Freud (1884)
| |
| | |
| and has been repeatedly confirmed in the
| |
| | |
| pharmacological literature:
| |
| | |
| At a high level of intoxication, central
| |
| | |
| excitation sets in with characteristic shivering,
| |
| | |
| an initial state of euphoria that turns into
| |
| | |
| delirium and hallucinations. For women, the
| |
| | |
| stimulation ... not infrequently has an erotic
| |
| | |
| character and has resulted in later accusations
| |
| | |
| of sexual misconduct against the operating
| |
| | |
| physician. (Fiihner 1943, 196*)
| |
| | |
| Some psychiatrists believe that cocaine stimulates
| |
| | |
| the "sexual center" of the brain (Siegel
| |
| | |
| 1982a). For many users, cocaine is inevitably
| |
| | |
| associated with sexuality (MacDonald et al. 1988;
| |
| | |
| Phillips and Wynne 1980,221).
| |
| | |
| Cocaine relaxes and opens the sphincter
| |
| | |
| muscles, which makes anal penetration easier as
| |
| | |
| well as substantially more pleasurable. However,
| |
| | |
| cocaine (much like ephedrine) often has an
| |
| | |
| adverse effect on erectile function and consequently
| |
| | |
| leads to temporary impotence (cf. Siegel
| |
| | |
| 1982a).
| |
| | |
| The addictive potential of cocaine has been the
| |
| | |
| subject of much debate. This issue does not appear
| |
| | |
| to be oriented toward the user as much as it
| |
| | |
| reflects the current legal situation. In recent years,
| |
| | |
| there have been efforts to develop a vaccination
| |
| | |
| against "cocaine addiction." Of course, the
| |
| | |
| research in this area is conducted on rats (Hellwig
| |
| | |
| 1996). The effect of cocaine on the brain is also an
| |
| | |
| object of much research, since studies that
| |
| | |
| confirm the adverse effects of cocaine are likely to
| |
| | |
| receive financial support from the government. Studies that do not have a political agenda are the
| |
| | |
| exception rather than the rule (Volkow and Swann
| |
| | |
| 1990).
| |
| | |
| People who use cocaine frequently suffer from
| |
| | |
| a runny nose ("coke sniffles") the following day.
| |
| | |
| Users may counteract this undesirable and
| |
| | |
| unpleasant aftereffect by rinsing their nose with a
| |
| | |
| saline solution (e.g., with medicinal salts). Many
| |
| | |
| users rub vitamin E oil in their nose, a practice
| |
| | |
| said to regenerate the highly irritated mucous
| |
| | |
| membranes in the nose (Voigt 1982,72). Although
| |
| | |
| cocaine can be very helpful in dealing with an
| |
| | |
| acute attack of hay fever, chronic use can actually
| |
| | |
| contribute to the condition.
| |
| | |
| <strong>Crack or Free-Base Cocaine</strong>
| |
| | |
| In the German press, crack has been portrayed as
| |
| | |
| "death for a few dollars," "the devil's drug from the
| |
| | |
| U.S.A.;' et cetera. The general idea seems to be that
| |
| | |
| "cocaine was a miracle, but crack, crack was better
| |
| | |
| than sex" or "cocaine was purgatory-but crack is
| |
| | |
| hell" (in Wiener 6 [1986]: 65,66).
| |
| | |
| Crack, which is also known as base, free base,
| |
| | |
| baseball, rocks, Roxanne, and supercoke, is
| |
| | |
| nothing more than smokeable free-base cocaine
| |
| | |
| (Siegel 1982b). In other words, crack is cocaine in
| |
| | |
| the form of a free base (Pulvirenti and Koob 1996,
| |
| | |
| 48). It can be obtained from an aqueous solution
| |
| | |
| of cocaine hydrochloride to which an alkaline
| |
| | |
| substance (such as sodium carbonate) is added.
| |
| | |
| The cocaine salt is transformed into the pure base,
| |
| | |
| or, in other words, the pure substance. It can then
| |
| | |
| be purified with ether, causing the cocaine to
| |
| | |
| crystallize out. Crack is usually "smoked" (i.e.,
| |
| | |
| vaporized and inhaled) in glass pipes. A typical
| |
| | |
| dosage ranges from 0.05 to 0.1 g. The effect is very
| |
| | |
| similar to that of snuffed cocaine but is much
| |
| | |
| more intense:
| |
| | |
| Although crack is a derivative of cocaine, there
| |
| | |
| is little comparison between the mild and
| |
| | |
| mostly stimulating cocaine inebriation and
| |
| | |
| the effects of the short-term crack high, which
| |
| | |
| can literally bowl one over. Whereas cocaine
| |
| | |
| produces a euphoric sensation of great concentration
| |
| | |
| and razor-sharp intelligence for
| |
| | |
| about 20 to 60 minutes, crack lasts for only
| |
| | |
| three to five minutes while giving the consumer
| |
| | |
| an incredibly strong kick with regard to
| |
| | |
| physical sensations as well as the euphoria of
| |
| | |
| absolute omnipotence. Of course, this has
| |
| | |
| resulted in many myths, including one that
| |
| | |
| crack is particularly pure. (Sahihi 1995,37*)
| |
| | |
| Ethnologists have begun using the field
| |
| | |
| methods typical of the discipline to study the
| |
| | |
| "crack phenomenon;' which appears to be a
| |
| | |
| typically American product (Holden 1989).
| |
| | |
| "Crack life" is a reflection of the problems in
| |
| | |
| American society and reveals deep social fissures and cultural anomalies. For users, the "crack way"
| |
| | |
| is an important form of identity formation. Crack
| |
| | |
| is frequently found together with prostitution, as
| |
| | |
| "addicts" may accept it as a form of payment for
| |
| | |
| sexual services (Carlson and Siegal 1991).
| |
| | |
| On the street, the following substances may be
| |
| | |
| used as substitutes for cocaine or crack in times of
| |
| | |
| shortage: procaine, caffeine, benzocaine, phenylpropanolamine,
| |
| | |
| lidocaine, and ephedrine (Siegel
| |
| | |
| 1980).
| |
| | |
| <strong>Commercial Forms and Regulations</strong>
| |
| | |
| Cocaine hydrochloride is available through the
| |
| | |
| pharmacy trade. The German Drug Law lists
| |
| | |
| cocaine as a "narcotic drug in which trafficking is
| |
| | |
| allowed but which may not be prescribed"
| |
| | |
| (Korner 1994, 42). In the United States, the Controlled
| |
| | |
| Substances Act classifies cocaine as a
| |
| | |
| Schedule II substance.
| |
| | |
| <strong>Literature</strong>
| |
| | |
| See also the entries for Erythroxylum coca,
| |
| | |
| Erythroxylum novogranatense, atropine, and
| |
| | |
| tropane alkaloids.
| |
| | |
| Ashley, Richard. 1975. Cocaine: Its history, use and
| |
| | |
| effects. New York: St. Martin's Press.
| |
| | |
| Aurep, B. von. 1880. Dber die physiologische
| |
| | |
| Wirkung des CocaYn. Archiv fur Physiologie
| |
| | |
| 21:38-77.
| |
| | |
| Badekerl, Klaus. 1983. Ein Kilo Schnee von Gestern.
| |
| | |
| Munich and Zurich: Piper.
| |
| | |
| Benn, Gottfried. 1982. Gedichte, in der Fassung der
| |
| | |
| Erstdrucke. Frankfurt/M.: Fischer.
| |
| | |
| Boye, Karin. 1986. Kallocain: Roman aus dem 21.
| |
| | |
| Jahrhundert. Kiel: Neuer Malik Verlag.
| |
| | |
| Biisch, H. P., and W. Rummel. 1990.
| |
| | |
| Lokalanasthetika, Lokalanasthesie. In Allgemeine
| |
| | |
| und spezielle Pharmakologie und Toxikologie (5th
| |
| | |
| ed.), ed. W. Forth, D. Heuschler, and W. Rummel,
| |
| | |
| 490-96. Mannheim, Vienna, and Zurich: B. 1.
| |
| | |
| Wissenschaftsverlag.
| |
| | |
| Carlson, Robert G., and Harvey A. Siegal. 1991. The
| |
| | |
| crack life: An ethnographic overview of crack use
| |
| | |
| and sexual behavior among African-Americans
| |
| | |
| in a Midwest metropolitan city. Journal of
| |
| | |
| Psychoactive Drugs 23 (1): 11-20.
| |
| | |
| Crowley, Aleister. 1973. Cocaine. San Francisco:
| |
| | |
| And/Or Press.
| |
| | |
| Custer, Julius, Jr. 1898. Cocain und
| |
| | |
| Infiltrationanasthesie. Basel: Benno Schwabe.
| |
| | |
| Ellis, Bret Easton. 1987. Less Than Zero. New York:
| |
| | |
| Random House.
| |
| | |
| Fauser, Jorg. 1983. Der Schneemann. Reinbek:
| |
| | |
| Rowohlt.
| |
| | |
| Fischer 5., A. Raskin, and E. Uhlenhuth, eds. 1987.
| |
| | |
| Cocaine: Clinical and biobehavioral aspects. New
| |
| | |
| York: Oxford University Press.
| |
| | |
| Freud, Sigmund. 1884. Uher Coca. Centralblatt fur
| |
| | |
| die gesamte Therapie 2:289-314. Repr. in
| |
| | |
| Taschner and Richtberg 1982,206-31 (see
| |
| | |
| below).
| |
| | |
| ---. 1885. Dber die Allgemeinwirkung des
| |
| | |
| Cocains. Medizinisch-chirurgisches Centralblatt
| |
| | |
| 20:374-75.
| |
| | |
| ---.1887. Bemerkungen tiber Cocainsucht und
| |
| | |
| Cocainfurcht, mit Beziehung auf einen Vortrag
| |
| | |
| von W. A. Hammonds. Wiener medizinische
| |
| | |
| Wochenschrift 37:927-32.
| |
| | |
| ---.1996. Schriften uber Kokain. Frankfurt/M.:
| |
| | |
| Fischer. (Orig. pub. 1884.)
| |
| | |
| Gay, George R. 1981. You've corne a long way, baby!
| |
| | |
| Coke time for the new American lady of the
| |
| | |
| eighties. Journal ofPsychoactive Drugs 13 (4):
| |
| | |
| 297-318.
| |
| | |
| Gottlieb, Adam. 1979. The pleasures ofcocaine. San
| |
| | |
| Francisco: And/Or Press.
| |
| | |
| Grinspoon, Lester, and James B. Bakalar. 1985.
| |
| | |
| Cocaine: A drug and its social evolution. Rev. ed.
| |
| | |
| New York: Basic Books.
| |
| | |
| Hartmann, Walter. 1990. Informationsreihe Drogen:
| |
| | |
| Kokain. Markt Erlbach: Raymond Martin Verlag.
| |
| | |
| Hellwig, Bettina. 1996. Impfung gegen Cocain?
| |
| | |
| Deutsche Apotheker-Zeitung 136 (4): 46/270.
| |
| | |
| Holden, Constance. 1989. Streetwise crack research.
| |
| | |
| Science 246:1376-81.
| |
| | |
| Holmstedt, Bo, Eva Jaatmaa, Kurt Leander, and
| |
| | |
| Timothy Plowman. 1977. Determination
| |
| | |
| of cocaine in some South American species of
| |
| | |
| Erythroxylum using mass fragmentography.
| |
| | |
| Phytochemistry 16:1753-55.
| |
| | |
| Kennedy, J. 1985. Coca exotics: The illustrated story of
| |
| | |
| cocaine. New York: Cornwall Books.
| |
| | |
| Koller, Carl [= Karl]. 1884. Dber die Verwendung des
| |
| | |
| CocaYn zur Anasthetisierung am Auge. Wiener
| |
| | |
| medizinische Wochenschrift 34: 1276-1278,
| |
| | |
| 1309-1l.
| |
| | |
| ---. 1935. Nachtragliche Bemerkungen tiber die
| |
| | |
| ersten Anfange der Lokalanasthesie. Wiener
| |
| | |
| medizinische Wochenschrift 85:7.
| |
| | |
| ---. 1941. History of cocaine as a local
| |
| | |
| anesthetic. Journal ofthe American Medical
| |
| | |
| Association 117: 1284.
| |
| | |
| Lindgren, J.-E. 1981. Guide to the analysis of cocaine
| |
| | |
| and its metabolites in biological material. Journal
| |
| | |
| ofEthnopharmacology 3:337-5l.
| |
| | |
| Lossen, W. 1865. Dber das Cocain. Liebig's Annalen
| |
| | |
| 133:351-71.
| |
| | |
| MacDonald, P. T., V. Waldorf, C. Reinarman, and
| |
| | |
| S. Murphy. 1988. Heavy cocaine use and sexual
| |
| | |
| behavior. Journal ofDrug Issues 18 (3): 437-55.
| |
| | |
| Maier, Hans Wolfgang. 1926. Der Kokainismus.
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| | |
| Leipzig: Thieme.
| |
| | |
| Mcinerney, Jay. 1984. Bright Lights, Big City. New
| |
| | |
| York: Knopf.
| |
| | |
| Morales, Edmundo. 1989. Cocaine: White gold rush in
| |
| | |
| Peru. Tucson and London: The University of
| |
| | |
| Arizona Press.
| |
| | |
| Niemann, Albert. 1860. Dber eine neue organische
| |
| | |
| Base in den Cocablattern. Dissertation,
| |
| | |
| Gottingen University.
| |
| | |
| Pernice, Ludwig. 1890. Dber Cocainanaesthesie.
| |
| | |
| Deutsche medizinische Wochenschrift 16:287.
| |
| | |
| Phillips, Joel 1., and Ronald D. Wynne. 1980.
| |
| | |
| Cocaine: The mystique and the reality. New York:
| |
| | |
| Avon Books.
| |
| | |
| Plasket, B., and E. Quillen. 1985. The white stuff. New
| |
| | |
| York: Dell Publishing Co.
| |
| | |
| Pulvirenti, Luigi, and George F. Koob. 1996. Die
| |
| | |
| Neurobiologie der Kokainabhangigkeit. Spektrum
| |
| | |
| der Wissenschaft 2:48-55. (An unethical and
| |
| | |
| nauseating study on animals.)
| |
| | |
| Rheiner, Walter. 1979. Kokain: Eine Novelle und
| |
| | |
| andere Prosa. Berlin and Darmstadt: Agora
| |
| | |
| Verlag. Repr. 2nd ed., 1982.
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| | |
| Richards, Eugene. 1994. Cocaine true, cocaine blue.
| |
| | |
| New York: Aperture.
| |
| | |
| Roles, R., M. Goldberg, and R. G. Sharrar. 1990. Risk
| |
| | |
| factors for syphilis: Cocaine use and prostitution.
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| | |
| American Journal ofPublic Health 80 (7): 853-57.
| |
| | |
| Sabbag, Robert. 1976. Snowblind: A briefcareer in the
| |
| | |
| cocaine trade. Indianapolis and New York: The
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| Bobbs-Merrill Co.
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| | |
| Sauloy, Mylene, and Yves Le Bonniec. 1994.
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| | |
| Tropenschnee-Kokain: Die Kartelle, ihre Banken,
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| | |
| ihre Gewinne. Ein Wirtschaftsreport. Reinbek bei
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| Hamburg: Rowohlt.
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| | |
| Siegel, Ronald K. 1978. Cocaine hallucinations.
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| | |
| American Journal ofPsychiatry 135:309-14.
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| ---.1980. Cocaine substitutes. New England
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| Journal ofMedicine 302:817-18.
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| | |
| ---. 1982a. Cocaine and sexual dysfunction: The
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| curse of Mama Coca. Journal ofPsychoactive
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| Drugs 14 (1-2): 71-74.
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| ---. 1982b. Cocaine smoking. Journal of
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| Psychoactive Drugs 14 (4): 271-359.
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| Smith, David E., and Donald R. Wesson. 1978.
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| Cocaine. Journal ofPsychedelic Drugs 10 (4):
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| 351-60.
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| Springer, Alfred, ed. 1989. Kokain: Mythos und
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| Realitiit-Eine kritisch dokumentierte Anthologie.
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| Vienna and Munich: Verlag Christian
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| Brandstatter.
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| Taschner, Karl-Ludwig, and Werner Richtberg. 1982.
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| Kokain-Report. Wiesbaden: Akademische
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| Verlagsgesellschaft.
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| Thamm, Berndt Georg. 1985. Das Kartell: Von
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| Drogen und Miirkten-ein modernes Miirchen.
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| Basel: Sphinx.
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| ---. 1986. Andenschnee: Die lange Linie des
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| Kokain. Basel: Sphinx.
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| Timmerberg, Helge. 1996. Kaltmacher Kokain.
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| Tempo 3:34-42.
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| Turner, Canton E., Beverly S. Urbanek, G. Michael
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| Wall, and Coy W. Waller. 1988. Cocaine: An
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| annotated bibliography. 2 vols. Jackson and
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| London: Research Institute of Pharmaceutical
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| Sciences/University Press of Mississippi.
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| Voigt, Hermann P. 1982. Zum Thema: Kokain. Basel:
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| Sphinx.
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| Volkow, Nora v., and Alan C. Swann, eds. 1990.
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| Cocaine in the brain. New Brunswick, N.J.:
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| Rutgers University Press. (See book review by
| |
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| Ronald Siegel in Journal ofPsychoactive Drugs 23
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| (1; 1991): 93 f.)
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| vom Scheidt, Jurgen. 1973. Freud und das Kokain.
| |
| | |
| Psyche (Munich) 27:385-430.
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| | |
| ---.1981. Kokain. In Rausch und Realitat, ed. G.
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| Volger, 1:398-402. Cologne: Rautenstrauch-Joest
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| Museum fur Volkerkunde.
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| Wesson, Donald R. 1982. Cocaine use by masseuses.
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| Journal ofPsychoactive Drugs 14 (1-2): 75-76.
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| Wolfer, P. 1922. Das Cocain, seine Bedeutung und
| |
| | |
| seine Geschichte. Schweizerische medizinische
| |
| | |
| Wochenschrift 3:674-79.</td>
| |
| </tr>
| |
| | |
| </table>
| |