Terminology

MXE

Methoxetamine

Agonist

agonist

A substance that initiates a physiological response when combined with a receptor.

Antagonist

antagonist

A substance that interferes with or inhibits the physiological action of another.

Cannabinoid

cannabinoid

Chemicals produced naturally that bind to cannabinoid receptors. They are involved in a variety of mental and physical processes, including pain regulation, food intake, and reward.

Cathinone

cathinone

Cathinone, or Benzoylethanamine is a monoamine alkaloid found in the shrub Catha edulis (khat) and is chemically similar to ephedrine, cathine and other amphetamines. Cathinone differs from amphetamine by possessing a ketone oxygen atom on the β position of the side chain.

Chiral

chiral

Chirality

chirality

The term chiral describes an object, especially a molecule, which has or produces a non-superimposeable mirror image of itself.

Dopamine

dopamine

A neurotransmitter associated with movement, attention, learning, and the brain’s pleasure and reward system.

Enantiomer

enantiomer

One of two stereoisomers that are mirror images of each other that are non-superposable (not identical). Think of it like the left and right hand, which are identical aside from orientation.

GABA

Gamma aminobutyric acid an amino acid that is found in the central nervous system; acts as an inhibitory neurotransmitter.

MAO

Monoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin).

MAOI

Monoamine oxidase inhibitor any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate.

Nootropics

nootropics

These are a class of drugs that work by increasing levels of either/or neurotransmitters, enzymes, hormones, oxygen supply, and/or stimulating nerve growth. They are generaly neuroprotective, and extremely non-toxic.

Norepinephrine

Norepinephrine, or noradrenaline, is a catecholamine with multiple roles including as a hormone and a neurotransmitter.

Phenethylamine

phenethylamine

Phenethylamine (PEA) is a natural monoamine alkaloid, trace amine, and psychoactive drug with stimulant effects. In the mammalian central nervous system, phenethylamine is believed to function as a neuromodulator or neurotransmitter.

Releaser

releaser

A releasing agent (RA), or simply releaser, is a drug that induces the release of a neurotransmitter from the presynaptic neuron into the synapse, leading to an increase in the extracellular concentrations of the neurotransmitter.

Serotonin

serotonin

A monoamine neurotransmitter, biochemically derived from tryptophan, that is primarily found in the gastrointestinal (GI) tract, platelets, and central nervous system (CNS) of humans and animals. It is a well-known contributor to feelings of well-being.

ROA

Common abbreviation for Route Of Administration, used to describe the various different methods of ingesting drugs, including oral, insufflation, sublingual/buccal, rectal, intramuscular (IM) and intravenous (IV) injection.

Isomer

isomer

Each of two or more compounds with the same formula but a different arrangement of atoms in the molecule and different properties.

DRI

Dopamine Reuptake Inhibitor

SSRI

Selective Serotonin Reuptake Inhibitor

NMDA

N-methyl-D-aspartate receptor

TAAR

Trace amine-associated receptor

Bruxism

Bruxing

bruxing

Grinding or clenching of the teeth

Ataxia

ataxia

Loss of motor coordination