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| 5-HTP
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| Dose
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| Light Theraputic (anxiety): 50mg-100mg Common Theraputic (sleep): 100mg-200mg Recovery Dose (ie comedown of MDMA) 200-300mg (excess of 300mg
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| Duration
| | https://www.reddit.com/r/DrugNerds/comments/15m9sf/mdma_supplementation |
| 4-6 hours
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| Onset
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| 30-60 minutes
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| Effects
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| Mood Stabilization, Euphoria, sleep aid, antidepressant, appetite suppressant, possible nausea
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| Avoid
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| Anything that interacts with serotonin levels or is serotonergic including SSRIs, MAOIs (in large doses), DXM, MDMA (during or before)
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| Aliases
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| 5HTP
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| 5-Hydroxytryptophan
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| Tryptophan
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| L-Tryptophan
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| oxitriptan
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| Summary
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| An amino acid that is the precursor to serotonin. 5-HTP is sold over the counter in the United Kingdom, the United States and Canada as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid. It is also useful in the recovery from certain psychedelics that drain serotonin such as MDMA (See ~drugs 5-HTP MDMA
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| Categories
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| Mood stabilizer, Anti-depressant, recovery
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| Half Life
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| The biological half-life of 5-HTP ranged from 2.2 to 7.4 hours, and the plasma clearance ranged from 0.10 to 0.23 1/kg/hour
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| After-Effects
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| Minimal, slight depression/anxiety after repeated use
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| MDMA
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| MDMA and 5-HTP are dangerous when done at the same time. However, 5-HTP can mean a world of difference for recovering from MDMA and other drugs.
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| One must use 5-HTP AFTER your MDMA high fades and the dysphoric comdown begins. Wait AT LEAST 5-6 hours after the last dose of MDMA.
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| The basis for doing this is that 5-HTP is a necessary precursor for the brain to produce more serotonin, and MDMA use depletes a person's natural serotonin levels, thus taking 5-HTP after consuming MDMA is speculated as helping improve serotonin production.
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