Amphetamine: Difference between revisions

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== General Information ==
[[File:Spaste.png|thumb|200px|left|Dried speed paste]]


Amphetamine is a CNS stimulant, producing mild euphoria and an abundance of energy.
Amphetamine is a CNS stimulant, producing mild euphoria and an abundance of energy. Amphetamines include both the specific chemical 'amphetamine' and the general class of chemicals which share structural similaries. Amphetamines generally cause strong physical and mental stimulation, keeping users awake and alert for many hours, and some amphetamines cause mood lift / euphoria. Because they increase wakefulness, various amphetamines have been used by the military, by pilots, truck drivers, and other workers to keep functioning past their normal limits.


=== History ===
Amphetamine was discovered in 1887 and exists as two enantiomers: levoamphetamine and dextroamphetamine. Amphetamine properly refers to the racemic free base, or equal parts of the enantiomers levoamphetamine and dextroamphetamine in their pure amine forms. Nonetheless, the term is frequently used informally to refer to any combination of the enantiomers, or to either of them alone.


[http://en.wikipedia.org/wiki/History_and_culture_of_amphetamines History and culture of amphetamines]
== Dosage ==


=== Images ===
Depending on purity, amphetamine doses '''will''' vary. Branded amphetamine, like [[Adderall]], knows similar yet better documented and thus more predictable doses.


[[File:Amphetamine-2D-skeletal.svg-220px.png|Chemical structure of amphetamine]]
{{#tdose: amphetamines}}


[[File:Amphetamine3D rendering.gif|3D model of amphetamine molecule]]
== Duration ==
[[File:Amphetamines.jpg|52mg of street amphetamines. US Dime for scale.]]


== Dosage ==
Some branded forms of amphetamine like [[Adderall]], generally purposed to be prescribed to treat ADD and ADHD, are extended release (XR), which increases the duration of a single administration.


(Note: Depending on purity, amphetamine dosage '''will''' vary)
{| class="wikitable"
|+ Oral
|-
| Onset || 15-30 minutes
|-
| Total || 2-4 hours
|}


=== Oral ===
{| class="wikitable"
|+ Insufflated
|-
| Onset || 1-5 minutes
|-
| Total || 1-3 hours
|}


Onset: 15-30 minutes
== Effects ==


Duration: 2-4 hours
=== Positive ===
 
Low dose: 25-40 mg
 
Common (typical) dose: 40-75 mg
 
Strong dose: 75-125 mg
 
Heavy dose: 125-175 mg
 
=== Insufflated ===
 
Onset: 1-5 minutes
 
Duration: 2-4 hours
 
Low dose: 15-25 mg
 
Common (typical) dose: 25-40 mg
 
Strong dose: 40-75 mg
 
Heavy dose: 75-100 mg
 
== Effects ==
 
=== Positive ===  


* Increased focus
* Increased focus
Line 67: Line 52:


* Tachycardia (Elevated heart rate)
* Tachycardia (Elevated heart rate)
* Hypertension (High blood pressure)
* Peripheral vasoconstriction (Blood vessels get smaller in hands and feet making them susceptible to damage from cold)


* Paranoia
* Paranoia


* Insomnia
* Irritability
 
* Insomnia (inability to fall asleep)


=== After effects ===
=== After effects ===
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* Recommended time (pauses) between using the substance
* Recommended time (pauses) between using the substance


== Detection Times ==
*Stimulant drugs can cause kidney damage and stroke in users with high blood pressure. If you have been diagnosed or told you have high blood pressure use with caution
 
See [[Stimulants#Harm_Reduction|Stimulant Harm Reduction]] for general information.
 
=== Detection Times ===


* Blood: 12 hours
* Blood: 12 hours
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* Urine: 1-4 days
* Urine: 1-4 days


== Legal Status==  
== Images ==
 
<gallery mode="packed-hover">
Image:Spaste.png|''Drying amphetamine paste''
Image:Amphetamine.jpg|''Amphetamine with vial''
Image:Amphetamines.JPG|''~50mg of amphetamine''
Image:Adderall.jpg|''Several 10mg [[Adderall]] IR pills''
</gallery>
 
== Legal status ==


* Canada: Schedule I
* Canada: Schedule I


* Great Britain: Class B
* UK: Class B


* Thailand: Category 1
* Thailand: Category 1


* United States: [http://www.justice.gov/dea/druginfo/ds.shtml Schedule II]
* United States: [http://www.justice.gov/dea/druginfo/ds.shtml Schedule II]
[[Category:Drugs]]
[[Category:Stimulant]]

Latest revision as of 19:02, 12 December 2017

Dried speed paste

Amphetamine is a CNS stimulant, producing mild euphoria and an abundance of energy. Amphetamines include both the specific chemical 'amphetamine' and the general class of chemicals which share structural similaries. Amphetamines generally cause strong physical and mental stimulation, keeping users awake and alert for many hours, and some amphetamines cause mood lift / euphoria. Because they increase wakefulness, various amphetamines have been used by the military, by pilots, truck drivers, and other workers to keep functioning past their normal limits.

Amphetamine was discovered in 1887 and exists as two enantiomers: levoamphetamine and dextroamphetamine. Amphetamine properly refers to the racemic free base, or equal parts of the enantiomers levoamphetamine and dextroamphetamine in their pure amine forms. Nonetheless, the term is frequently used informally to refer to any combination of the enantiomers, or to either of them alone.

Dosage

Depending on purity, amphetamine doses will vary. Branded amphetamine, like Adderall, knows similar yet better documented and thus more predictable doses.

{{#tdose: amphetamines}}

Duration

Some branded forms of amphetamine like Adderall, generally purposed to be prescribed to treat ADD and ADHD, are extended release (XR), which increases the duration of a single administration.

Oral
Onset 15-30 minutes
Total 2-4 hours
Insufflated
Onset 1-5 minutes
Total 1-3 hours

Effects

Positive

  • Increased focus
  • Abundance of energy
  • Increased motivation

Negative

  • Racing thoughts
  • Reduced appetite
  • Flushing of the face
  • Increased body temperature
  • Tachycardia (Elevated heart rate)
  • Hypertension (High blood pressure)
  • Peripheral vasoconstriction (Blood vessels get smaller in hands and feet making them susceptible to damage from cold)
  • Paranoia
  • Irritability
  • Insomnia (inability to fall asleep)

After effects

  • Hangover
  • Afterglow
  • Restlessness
  • Persisting stimulation (5-15 hours after last dose.)

Harm Reduction

  • Avoid driving and operating heavy machinery
  • Recommended time (pauses) between using the substance
  • Stimulant drugs can cause kidney damage and stroke in users with high blood pressure. If you have been diagnosed or told you have high blood pressure use with caution

See Stimulant Harm Reduction for general information.

Detection Times

  • Blood: 12 hours
  • Hair: 90 days
  • Saliva: 3 days
  • Urine: 1-4 days

Images

Legal status

  • Canada: Schedule I
  • UK: Class B
  • Thailand: Category 1