Hydromorphone: Difference between revisions

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== General information ==
[[File:2000px-Hydromorphone - Hydromorphon.svg.png|280px|right]]


Hydromorphone, usually sold as brand names Palladone or Dilaudid, is a very potent centrally acting analgesic drug of the opioid class.  
'''Hydromorphone''', a more common synonym for dihydromorphinone (not to be confused by dihydromorphine, which is a different derivative of the morphine family), commonly a hydrochloride (brand names Palladone, Dilaudid, and numerous others). It's a semi-synthetic opioid.


=== History ===
== History ==


Knoll introduced it to the mass market in 1926 under the brand name Dilaudid, indicating its derivation and degree of similarity to morphine (by way of laudanum). The brand name Dilaudid is more widely known than the generic term hydromorphone, and because of this, Dilaudid is often used generically to mean any form of hydromorphone.
Knoll introduced it to the mass market in 1926 under the brand name Dilaudid, indicating its derivation and degree of similarity to morphine (by way of laudanum). The brand name Dilaudid is more widely known than the generic term hydromorphone, and because of this, Dilaudid is often used generically to mean any form of hydromorphone.


=== Images ===  
== Dosage ==
 
=== Oral ===
{| class="wikitable"
| Light || 1-2 mg
|-
| Common || 3-4mg
|-
| Strong || 4-8mg+
|}
 
=== Insufflated ===
{| class="wikitable"
| Light || 1-2mg
|-
| Common || 3-4mg
|-
| Strong || 4-8mg+
|}
 
=== Intravenous ===
{| class="wikitable"
| Light || 1-2mg
|-
| Common || 2-4mg
|-
| Strong || 4-6mg+
|}
 
 
 
== Duration ==
 
=== Oral ===
 
{| class="wikitable"
|-
| Ora
|-
| Onset 20-40 minutes.
|-
| Total: 3-4 hours.
|}
 
 
=== Insufflated ===
 
{| class="wikitable"
|-
| Insufflated
|-
| Onset: 5-10 minutes.
|-
| Total: 2-3 hours.
|}
 
 
=== Intravenous ===
 
{| class="wikitable"
|-
| Intravenous
|-
| Onset Instant
|-
| Total: 1-2 hours.
|}
 
== Effects ==
 
=== Positive ===
 
* Euphoria
 
* Pain relief
 
=== Neutral ===
 
* Pupil Constriction
 
* Itching
 
* Sedation
 
=== Negative ===
 
* Drowsiness
 
* CNS depression
 
* Dizziness
 
* Nausea
 
* Vomiting
 
* Constipation
 
* Sweating


[[File:2000px-Hydromorphone - Hydromorphon.svg.png|300px|Chemical structure of hydromorphone]]
== Legal status ==


[[File:Hydromorphone 27feb.gif|3D animated model of a hydromorphone molecule]]
* United States: Illegal to buy, sell, and possess without a prescription [http://www.justice.gov/dea/druginfo/ds.shtml Schedule II]


== Dosage ==
[[Category:Drugs]]


== Legal Status ==
[[Category:Opioid]]


* United States: [http://www.justice.gov/dea/druginfo/ds.shtml Schedule II]
[[Category:Depressant]]

Latest revision as of 01:08, 19 June 2016

Hydromorphone, a more common synonym for dihydromorphinone (not to be confused by dihydromorphine, which is a different derivative of the morphine family), commonly a hydrochloride (brand names Palladone, Dilaudid, and numerous others). It's a semi-synthetic opioid.

History

Knoll introduced it to the mass market in 1926 under the brand name Dilaudid, indicating its derivation and degree of similarity to morphine (by way of laudanum). The brand name Dilaudid is more widely known than the generic term hydromorphone, and because of this, Dilaudid is often used generically to mean any form of hydromorphone.

Dosage

Oral

Light 1-2 mg
Common 3-4mg
Strong 4-8mg+

Insufflated

Light 1-2mg
Common 3-4mg
Strong 4-8mg+

Intravenous

Light 1-2mg
Common 2-4mg
Strong 4-6mg+


Duration

Oral

Ora
Onset 20-40 minutes.
Total: 3-4 hours.


Insufflated

Insufflated
Onset: 5-10 minutes.
Total: 2-3 hours.


Intravenous

Intravenous
Onset Instant
Total: 1-2 hours.

Effects

Positive

  • Euphoria
  • Pain relief

Neutral

  • Pupil Constriction
  • Itching
  • Sedation

Negative

  • Drowsiness
  • CNS depression
  • Dizziness
  • Nausea
  • Vomiting
  • Constipation
  • Sweating

Legal status

  • United States: Illegal to buy, sell, and possess without a prescription Schedule II
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