Vyvanse is the brand name for the pharmaceutical stimulant lisdexamfetamine, a prodrug for dexamphetamine. It was reported to be the 7th most prescribed drug recently according to a doctor who writes for WebMD, and is designed to limit methods of abuse such as other routes of administration. Vyvanse, being a prodrug, must be taken orallyRoute of administration in which the subject swallows a substance. in order to go through first pass metabolism to become dexamphetamine. Implications of this mean that it cannot be snorted and may not work via IV or other ROACommon abbreviation for Route Of Administration, used to describe the various different methods of ingesting drugs, including oral, insufflation, sublingual/buccal, rectal, vaginal, intramuscular (IM) and intravenous (IV) injection.'s besides oral. It has nearly identical effects to Dexedrine and Adderall, however has a smoother come up and less of a crash according to anecdotal reports from multiple drug forums and from users within the tripsit community. Being a stimulant it has various physical and mental side effects such as a raise in heart rate and blood pressure, racing thoughts, increased focus, sweating. and many more psychological and physical effects. See the effects section of this wiki article for more information on side effects.