Quick Guide to Uncommon Stimulants: Difference between revisions

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2-MDP - Dissociative anaesthetic, NMDA antagonist, simlar effects to PCP in animals, (-) isomer is active. Roughly 1/3rd  
:2-MDP - Dissociative anaesthetic, NMDA antagonist, simlar effects to PCP in animals, (-) isomer is active. Roughly 1/3rd potency of amphetamine by weight. Lasts over 24 hours.


potency of amphetamine by weight. Lasts over 24 hours.  
:2C-B-BZP - Benzylpiperazine base with ring-sub pattern of 2c-b. Not a phenethylamine, doesn't produce psychedelic effects. Lasts 3-6 hours. Was sold in Japan in "smartshops"


2C-B-BZP - Benzylpiperazine base with ring-sub pattern of 2c-b. Not a phenethylamine, doesn't produce psychedelic effects.  
:A-366/833 - Agonist at neural nicotinic acetylcholine receptors selective for α4β2 subtype. Been researched as an analgesic. Hasn't passed clinical trials.  


Lasts 3-6 hours. Was sold in Japan in "smartshops"  
:A-84/543 ^ That and is used as the "standard" for this family of compounds.


A-366/833 - Agonist at neural nicotinic acetylcholine receptors selective for α4β2 subtype. Been researched as an analgesic.  
:2-Acetoxycocaine - Quicker onset than Cocaine. Four fold increase over cocaine in binding potency for dopamine. And 35 fold enhanced affinity for the norepinephrine. Reduced selectivity for serotonin. Interesting structure.  


Hasn't passed clinical trials.  
:Adrafinil - Prodrug of Modafinil, unregulated in the US. 1 hour half life.  


A-84/543 ^ That and is used as the "standard" for this family of compounds.  
:AL-1095 - Centrally acting, comparable effects to amp. developed by Bristol in the 70's.  


2-Acetoxycocaine - Quicker onset than Cocaine. Four fold increase over cocaine in binding potency for dopamine. And 35 fold
:Altinicline (SIB-1508Y) agonist at neural nicotinic acetylcholine receptors similar to A-366. Releases Dopamine and Acetylcholine in both rodent and primate models. Progressed into Phase 2 clinical trials for Parkinson's.


enhanced affinity for the norepinephrine. Reduced selectivity for serotonin. Interesting structure.  
:Amfepramone - Diethylcathinone. By itself lacks any affinity for monoamine transporters and functions as a prodrug to ethcathinone. Very weak dopaminergic and serotonergic. 10-20x stronger on norepinephrine in comparison. Basically can be considered NRA's. Is currently Schedule IV in the United States. Class C drug in the UK. Apparently known as "tombstones" in the UK.  


Adrafinil - Prodrug of Modafinil, unregulated in the US. 1 hour half life.  
:2-amino-1,2-dihydronaphthalene - Also known as 2-AD, rigid analogue of phenylisobutylamine and substitutes amphetamine for it in rat discrimination tests, 1/4th the potency. Closely related to 2-aminotetralin.  


AL-1095 - Centrally acting, comparable efffects to amp. developed by Bristol in the 70's.  
:2-Aminoindane - 2-AI(RC) Psychoactive compound. Rigid analogue of amphetamine.  


Altinicline (SIB-1508Y) agonist at neural nicotinic acetylcholine receptors similar to A-366. Releases Dopamine and  
:5-(2-aminopropyl)indole - 5-IT(RC) indole derivative. Preparation was first reported in 1962 by Albert Hofmann. Positional isomer of AMT. Closer chemically resembles Phethylamines like 5-apb and the likes. Falls under the Analog act in the US with AMT.


Acetylcholine in both rodent and primate models. Progressed into Phase 2 clinical trials for Parkinson's.
:6-(2-Aminopropyl)indole - ^. But it has been shown to increase hemoglobin levels in the bloodstream.  


Amfepramone - Diethylcathinone. By itself lacks any affinity for monoamine transporters and functions as a prodrug to ethcathinone. Very weak dopaminergic and serotonergic. 10-20x stronger on norepinephrine in comparison. Basically can be considered NRA's. Is currently Schedule IV in the United States. Class C drug in the UK. Apparently known as "tombstones" in the UK.
:Aminorex - Known by many other names. Anorectic stimulant. Is classed within the 2-amino-5-aryl oxazoline class. Closely related to 4-methylaminorex. Shown to have locomotor stimulant effects, lying midway between dextro-amp and Meth. Attributed to the release of cathecholamines. Retired from the market after it was found to result in pulmonary hypertension.
 
:2-Aminotetralin - (2-AT) consiting of a tetralin group combined with an anime. Rigid analogue of phenylisobutylamine. Fully substitutes for D-Amp in rat discrimination tests. Although at 1/8th the potency. Inhibits the reuptake of serotonin and norepinephrine. Likely induces their release as well. Also likely to act of Dopamine on account of the D-Amp.
 
:Amiphenazole - Traditionally used as an antidote for Barb/opioid overdose. Mixed with bemegride. As well as poisoning from other depressants.
 
:Ampyzine - Pyrazine derivative. That's all I could find with my limited research.
 
:AR-R17779 - Drug that acts as a potent and selective full agonist for the α7 subtype of neural nicotinic acetylcholine receptors. Nootropic effects in animal sudies.
 
:Armodafinal - Basically like all other versions of the ***final's nothing popped very interesting.
 
:Bemegride - Used in barb overdoses. "Popularized" by The suspected Serial Killer Dr. John Bodkin Adams.
 
:Benocyclidine - (BCP/BTCP) RC of the arylcyclohexylamine class. Acts as a Potent and Selective DRI. Pure DRI with negligible affintity for NMDA. Lacks every other propeties in effects, minus stimulant. Found in several MDMA presses.
 
:3-benzhydrylmorpholine - Developed in the 50's by American Home Products Corp. Stimulant and anoretctic effects. Related to pipradrol and phenmetrazine.
 
:Benzofuranylpropylaminopentance - ((-)-BPAP) Catecholaminergic and Serotonergic activity enhancer. Only increases the amount of neurotransmitters that get released. Weak MAO-A inhibitor. Showen to have neuroprotective effects similar to selegiling.  
 
:Benzooylthiomethylecgonine - Cocaine Analogue which has a sulfur in place of an oxygen on the single bonded benzoyl ester. Thus lowering potency.
 
:1-Benzyl-4-(2-(diphenylmethoxy)ethyl)piperidine - Acts as a potent and selective DRI.  
 
:Benzylpipeazine - BZP, that's about it.
 
:2-benzylpipeazine - 20x less potent than MPH and desoxypipadrol. Synthetic intermediate in other drugs :o. Boring stuff.
 
:4-benzylpipeazine - The exact opposite of ^^. Acts as a MAOI with 20 to 48 fold selectivity for releasing dopamine versus serotonin.
 
:Brasofensine - Phehyltropane. Effective in stimulating LMA and reversing akinesia. Idunknow.   
 
:Bromantane - Stimulant with anxiolytic properties developed in Russia during the late 1980's. DSRI. Has an anticholinergic effect at very high doses. Used as a doping agent for athletic performance. No withdrawal symptoms!
 
:BTS 74,398 - Weird structure, centrally acting stimulant drug. Acts as a triple reuptake inhibitor.
 
:Butylolylquinuclidine - Was made to replace cocaine in cocaine addiction, while longest lasting and less potent.
 
:Camfetamine - N-Methyl homologue of fencamfamine. Apparently replaced mephedrone after it's banning?
 
:Meta-Chlorophenylpiperazine
 
:Cilboamine - NDRI, has stimulant and anti-dep effects.
 
:Clofeniciclan - Dopamine-releasing agent developed in the 50's. Proved unpopular as a treatment because of its pronounced stimulant activity

Latest revision as of 22:18, 3 February 2014

2-MDP - Dissociative anaesthetic, NMDA antagonist, simlar effects to PCP in animals, (-) isomer is active. Roughly 1/3rd potency of amphetamine by weight. Lasts over 24 hours.
2C-B-BZP - Benzylpiperazine base with ring-sub pattern of 2c-b. Not a phenethylamine, doesn't produce psychedelic effects. Lasts 3-6 hours. Was sold in Japan in "smartshops"
A-366/833 - Agonist at neural nicotinic acetylcholine receptors selective for α4β2 subtype. Been researched as an analgesic. Hasn't passed clinical trials.
A-84/543 ^ That and is used as the "standard" for this family of compounds.
2-Acetoxycocaine - Quicker onset than Cocaine. Four fold increase over cocaine in binding potency for dopamine. And 35 fold enhanced affinity for the norepinephrine. Reduced selectivity for serotonin. Interesting structure.
Adrafinil - Prodrug of Modafinil, unregulated in the US. 1 hour half life.
AL-1095 - Centrally acting, comparable effects to amp. developed by Bristol in the 70's.
Altinicline (SIB-1508Y) agonist at neural nicotinic acetylcholine receptors similar to A-366. Releases Dopamine and Acetylcholine in both rodent and primate models. Progressed into Phase 2 clinical trials for Parkinson's.
Amfepramone - Diethylcathinone. By itself lacks any affinity for monoamine transporters and functions as a prodrug to ethcathinone. Very weak dopaminergic and serotonergic. 10-20x stronger on norepinephrine in comparison. Basically can be considered NRA's. Is currently Schedule IV in the United States. Class C drug in the UK. Apparently known as "tombstones" in the UK.
2-amino-1,2-dihydronaphthalene - Also known as 2-AD, rigid analogue of phenylisobutylamine and substitutes amphetamine for it in rat discrimination tests, 1/4th the potency. Closely related to 2-aminotetralin.
2-Aminoindane - 2-AI(RC) Psychoactive compound. Rigid analogue of amphetamine.
5-(2-aminopropyl)indole - 5-IT(RC) indole derivative. Preparation was first reported in 1962 by Albert Hofmann. Positional isomer of AMT. Closer chemically resembles Phethylamines like 5-apb and the likes. Falls under the Analog act in the US with AMT.
6-(2-Aminopropyl)indole - ^. But it has been shown to increase hemoglobin levels in the bloodstream.
Aminorex - Known by many other names. Anorectic stimulant. Is classed within the 2-amino-5-aryl oxazoline class. Closely related to 4-methylaminorex. Shown to have locomotor stimulant effects, lying midway between dextro-amp and Meth. Attributed to the release of cathecholamines. Retired from the market after it was found to result in pulmonary hypertension.
2-Aminotetralin - (2-AT) consiting of a tetralin group combined with an anime. Rigid analogue of phenylisobutylamine. Fully substitutes for D-Amp in rat discrimination tests. Although at 1/8th the potency. Inhibits the reuptake of serotonin and norepinephrine. Likely induces their release as well. Also likely to act of Dopamine on account of the D-Amp.
Amiphenazole - Traditionally used as an antidote for Barb/opioid overdose. Mixed with bemegride. As well as poisoning from other depressants.
Ampyzine - Pyrazine derivative. That's all I could find with my limited research.
AR-R17779 - Drug that acts as a potent and selective full agonist for the α7 subtype of neural nicotinic acetylcholine receptors. Nootropic effects in animal sudies.
Armodafinal - Basically like all other versions of the ***final's nothing popped very interesting.
Bemegride - Used in barb overdoses. "Popularized" by The suspected Serial Killer Dr. John Bodkin Adams.
Benocyclidine - (BCP/BTCP) RC of the arylcyclohexylamine class. Acts as a Potent and Selective DRI. Pure DRI with negligible affintity for NMDA. Lacks every other propeties in effects, minus stimulant. Found in several MDMA presses.
3-benzhydrylmorpholine - Developed in the 50's by American Home Products Corp. Stimulant and anoretctic effects. Related to pipradrol and phenmetrazine.
Benzofuranylpropylaminopentance - ((-)-BPAP) Catecholaminergic and Serotonergic activity enhancer. Only increases the amount of neurotransmitters that get released. Weak MAO-A inhibitor. Showen to have neuroprotective effects similar to selegiling.
Benzooylthiomethylecgonine - Cocaine Analogue which has a sulfur in place of an oxygen on the single bonded benzoyl ester. Thus lowering potency.
1-Benzyl-4-(2-(diphenylmethoxy)ethyl)piperidine - Acts as a potent and selective DRI.
Benzylpipeazine - BZP, that's about it.
2-benzylpipeazine - 20x less potent than MPH and desoxypipadrol. Synthetic intermediate in other drugs :o. Boring stuff.
4-benzylpipeazine - The exact opposite of ^^. Acts as a MAOI with 20 to 48 fold selectivity for releasing dopamine versus serotonin.
Brasofensine - Phehyltropane. Effective in stimulating LMA and reversing akinesia. Idunknow.
Bromantane - Stimulant with anxiolytic properties developed in Russia during the late 1980's. DSRI. Has an anticholinergic effect at very high doses. Used as a doping agent for athletic performance. No withdrawal symptoms!
BTS 74,398 - Weird structure, centrally acting stimulant drug. Acts as a triple reuptake inhibitor.
Butylolylquinuclidine - Was made to replace cocaine in cocaine addiction, while longest lasting and less potent.
Camfetamine - N-Methyl homologue of fencamfamine. Apparently replaced mephedrone after it's banning?
Meta-Chlorophenylpiperazine
Cilboamine - NDRI, has stimulant and anti-dep effects.
Clofeniciclan - Dopamine-releasing agent developed in the 50's. Proved unpopular as a treatment because of its pronounced stimulant activity