General Information

Classification: Opiate/Downer/Sedative/Painkiller


Oxycodone, a strong and addictive drug used to treat moderate to severe pain. It is an analgesic medication synthesized from poppy-derived thebaine. It was developed in 1916 in Germany, as one of several new semi-synthetic opioids in an attempt to improve on the existing opioids: morphine, diacetylmorphine (heroin), and codeine. Oxycodone is available in the forms of instant release, paired with Acetaminophen, or extended release.


The following refer to oxycodone in the form of a drug such as Roxicet or Percosets. This does not apply to XR Oxycodone in the form of a drug like OxyContin which has a time release mechanism. Oxycodone can be taken orallyRoute of administration in which the subject swallows a substance., insufflated, or IVed (which is extremely dangerous.)


  • 5mg-20mg (No tolerance)
  • 20mg-60mg (Medium-High tolerance)
  • 60mg-120mg (Very High tolerance)
  • 120mg+ (Extremely High tolerance, potentially fatal for new users)

Any dose of Oxycodone may be fatal. Do not mix with other drugs or alcohol.


  • Oral: 20-40 minutes
  • Insufflated: Near Instantly (5-20 seconds)
  • IV: Instantly

Peak Benefit:

  • Oral: 30-60 minutes
  • Insufflated: 5-15 minutes
  • IV: 2-5 minutes
  • Half-life depends on a lot of factors such as weight, BMI, and metabolism.

Half/Life and Duration

Half-life = 3-4.5 hours

Duration depends upon R.O.A., as IVing will last much shorter, but with a more intense high, yet taking your Oxycodone orallyRoute of administration in which the subject swallows a substance. will be much more mellow feeling accompanied by a lesser "rush" feeling. but last longer.

Dosages Depend on tolerance.


The following products may react negatively with oxycodone and may cause overdose if mixed together.

  • Grapefruit juice:
  • Alcohol
  • Diphenhydramine


Excessive alcohol/grapefruit juice (drinking while taking oxycodone, especially drugs that contain APAP, such as percocet) can cause liver damage, other severe medical conditions, and even death. These potentiators may potentiate Oxycodone dangerously high for someone with a low-tolerance.





After effects

Harm Reduction

-Do not consume alcohol while under the influence of Oxycodone

Chemistry and Pharmacology





  • Oxycodone is subject to international conventions on narcotic drugs. In addition, oxycodone is subject to national laws that differ by country. The 1931 Convention for Limiting the Manufacture and Regulating the Distribution of Narcotic Drugs of the League of Nations included oxycodone.[45] The 1961 Single Convention on Narcotic Drugs of the United Nations, which replaced the 1931 convention, categorized oxycodone in Schedule I.[46] Global restrictions on Schedule I drugs include "limit[ing] exclusively to medical and scientific purposes the production, manufacture, export, import, distribution of, trade in, use and possession of" these drugs; "requir[ing] medical prescriptions for the supply or dispensation of [these] drugs to individuals"; and "prevent[ing] the accumulation" of quantities of these drugs "in excess of those required for the normal conduct of business".


  • Oxycodone is in Schedule I (derived from the Single Convention on Narcotic Drugs) of the Commonwealth's Narcotic Drugs Act 1967.[47] In addition, it is in Schedule 8 of the Australian Standard for the Uniform Scheduling of Drugs and Poisons ("Poisons Standard"), meaning it is a "controlled drug... which should be available for use but require[s] restriction of manufacture, supply, distribution, possession and use to reduce abuse, misuse and physical or psychological dependence".


  • Oxycodone is a controlled substance under Schedule I of the Controlled Drugs and Substances Act (CDSA).


"United Nations conference for the adoption of a single convention on narcotic drugs. Final act" (PDF). 1961. Retrieved 2009-04-04.

^ Commonwealth of Australia. "Narcotic Drugs Act 1967 – first schedule". Australasian Legal Information Institute. Retrieved 2009-04-06. ^ Australian Government. Department of Health and Aging. Therapeutic Goods Administration (June 2008). Standard for the uniform scheduling of drugs and poisons no. 23 (PDF). Canberra: Commonwealth of Australia. ISBN 1-74186-596-4. Retrieved 2009-04-06. ^ Canada Department of Justice (2009-02-27). "Controlled Drugs and Substances Act (1996, c. 19)". Retrieved 2009-03-23.


-Schedule 2, available only by prescription


-Presumably illegal

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