Contents General Information Dosage Harm Reduction

General Information

Methoxamine is a near chemical analogue of Ketamine and PCP. It was first publicly reported in 2010. Some say it's similar to Ketamine or a high dose DXM. It has been shown to act as an NMDAN-methyl-D-aspartate receptor. NMDA antagonists are often dissociatives. receptor antagonistA substance that interferes with or inhibits the physiological action of another. and SerotoninA monoamine neurotransmitter, biochemically derived from tryptophan, that is primarily found in the gastrointestinal (GI) tract, platelets, and central nervous system (CNS) of humans and animals. It is a well-known contributor to feelings of well-being. Re uptake Inhibitor. The N-Ethyl group on this compound increases potency.



  • Threshold 5-20mg's
  • Low 10-30mg's
  • Common 40-60mg's
  • Strong 50-100mg's+


  • Threshold 5-15mg's
  • Low 15-30mg's
  • Medium 30-50mg's
  • Strong 50-75mg's
  • Hole 75-100mg's+


  • Threshold 5-10mg's
  • Low 10-25mg's
  • Medium 40-60mg's
  • Strong 60-75mg's
  • Hole 75-100mg's

Harm Reduction

  • Avoid driving at all costs
  • Avoid walking or moving around in general if you are on a medium to hole dose.
  • Taking this on a non-empty substance could lead to nausea.

Top Contributors