Dissociatives - Revision history

Lightning po at 03:28, 27 May 2020

2020-05-27T03:28:46Z

← Older revision		Revision as of 22:28, 26 May 2020
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	*Driving or operating machinery under the influence of dissociatives is strongly discouraged. Your spatial awareness is extremely limited, even when mildly intoxicated.		*Driving or operating machinery under the influence of dissociatives is strongly discouraged. Your spatial awareness is extremely limited, even when mildly intoxicated.
	*On higher doses coordination is ~~impared~~ to the point that any movement should be as limited as possible. A safe environment without hazards is recommended (such as a bed). Most of the damage imparted by dissociatives are through users hurting themselves while attempting to move around while impaired.		*On higher doses coordination is impaired to the point that any movement should be as limited as possible. A safe environment without hazards is recommended (such as a bed). Most of the damage imparted by dissociatives are through users hurting themselves while attempting to move around while impaired.
	*Nausea can happen on many dissociatives, usually directly after dosing - usually only if there are stomach contents. It is best to not eat for 3-4 hours before dosing.		*Nausea can happen on many dissociatives, usually directly after dosing - usually only if there are stomach contents. It is best to not eat for 3-4 hours before dosing.
	*Dissociatives may be neurotoxic.<ref>http://dx.doi.org/10.1126%2Fscience.2660263</ref> Moderation is advised.		*Dissociatives may be neurotoxic.<ref>http://dx.doi.org/10.1126%2Fscience.2660263</ref> Moderation is advised.

Lightning po: /* Harm Reduction */ small spelling mistakes

2020-05-27T03:28:14Z

Harm Reduction: small spelling mistakes

← Older revision		Revision as of 22:28, 26 May 2020
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	*Driving or operating machinery under the influence of dissociatives is strongly discouraged. Your spatial awareness is extremely limited, even when mildly intoxicated.		*Driving or operating machinery under the influence of dissociatives is strongly discouraged. Your spatial awareness is extremely limited, even when mildly intoxicated.
	*On higher ~~does~~ coordination is ~~imparted~~ to the point that any movement should be as limited as possible. A safe environment without hazards is recommended (such as a bed). Most of the damage imparted by dissociatives are through users hurting themselves while attempting to move around while impaired.		*On higher doses coordination is impared to the point that any movement should be as limited as possible. A safe environment without hazards is recommended (such as a bed). Most of the damage imparted by dissociatives are through users hurting themselves while attempting to move around while impaired.
	*Nausea can happen on many dissociatives, usually directly after dosing - usually only if there are stomach contents. It is best to not eat for 3-4 hours before dosing.		*Nausea can happen on many dissociatives, usually directly after dosing - usually only if there are stomach contents. It is best to not eat for 3-4 hours before dosing.
	*Dissociatives may be neurotoxic.<ref>http://dx.doi.org/10.1126%2Fscience.2660263</ref> Moderation is advised.		*Dissociatives may be neurotoxic.<ref>http://dx.doi.org/10.1126%2Fscience.2660263</ref> Moderation is advised.

Toasterlizard: Reverted edits by Dumbdumb123 (talk) to last revision by Sleep

2018-10-09T22:09:13Z

Reverted edits by Dumbdumb123 (talk) to last revision by Sleep

← Older revision		Revision as of 17:09, 9 October 2018
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	~~=Goodbye moonmen=~~		[[File:Ketaminedxomxepcp.png\|200px\|thumb\|right]]
			'''Dissociatives''' are a class of [[hallucinogen]] which reduce or block signals to the conscious mind from other parts of the brain. In comparison to [[psychedelics]] and [[deliriants]], they are a very new class of hallucinogen, with the first classical dissociative being synthesized in 1926 (PCP). They offer a trip that is characterised by dissociation and bizarre feelings of detachment from reality, with anaesthetic-like effects and dream-like states.

			This guide is in reference to all of the classical Dissociatives, or more specifically, [[Ketamine]], [[MXE]], [[DXM]], [[PCP]] and [[3-MeO-PCP]]. This list excludes [[Nitrous Oxide]], which feels completely atypical in comparison.

			It’s worth noting that Dissociatives can be addictive and bad for your health with regular long-term usage, so you’ll need to do some independent research before trying these. Although these hallucinations are completely different to anything found with psychedelics, they should not be underestimated, and allow you to go equally as "deep" in a completely different mental landscape. However, they are not nearly as powerful when it comes to introspection and resolving personal problems.

			All of the classical Dissociatives are pharmacologically categorised as [[NMDA receptor]] antagonists, which are a class of anaesthetics that work to antagonise, or inhibit the action of, the N-methyl d-aspartate receptor (NMDAR). The NMDA receptor is a receptor that allows for the transfer of electrical signals between neurones in the brain and in the spinal column. These receptors are located at the end of dendrites on a neurone cell. The dendrites send messages to other neurones through these, but when a drug that blocks the NMDA activity is taken, they are partially or entirely blocked, decreasing the brain's ability to transfer information across itself. Disconnecting the neurones and causing feelings of extreme dissociation or detachment, leading to hallucinatory states. Causing states of moderate to extreme dissociation in the user as the subconscious brain begins to fill in these sensory gaps with entirely imagined hallucinations and dreamlike states.

	==Common Dissociatives==		==Common Dissociatives==

Dumbdumb123: Goodbye moonmen

2018-10-09T22:03:06Z

Goodbye moonmen

← Older revision		Revision as of 17:03, 9 October 2018
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	~~[[File:Ketaminedxomxepcp.png\|200px\|thumb\|right]]~~		=Goodbye moonmen=
	'''Dissociatives''' are a class of [[hallucinogen]] which reduce or block signals to the conscious mind from other parts of the brain. In comparison to [[psychedelics]] and [[deliriants]], they are a very new class of hallucinogen, with the first classical dissociative being synthesized in 1926 (PCP). They offer a trip that is characterised by dissociation and bizarre feelings of detachment from reality, with anaesthetic-like effects and dream-like states.

	This guide is in reference to all of the classical Dissociatives, or more specifically, [[Ketamine]], [[MXE]], [[DXM]], [[PCP]] and [[3-MeO-PCP]]. This list excludes [[Nitrous Oxide]], which feels completely atypical in comparison.

	It’s worth noting that Dissociatives can be addictive and bad for your health with regular long-term usage, so you’ll need to do some independent research before trying these. Although these hallucinations are completely different to anything found with psychedelics, they should not be underestimated, and allow you to go equally as "deep" in a completely different mental landscape. However, they are not nearly as powerful when it comes to introspection and resolving personal problems.

	All of the classical Dissociatives are pharmacologically categorised as [[NMDA receptor]] antagonists, which are a class of anaesthetics that work to antagonise, or inhibit the action of, the N-methyl d-aspartate receptor (NMDAR). The NMDA receptor is a receptor that allows for the transfer of electrical signals between neurones in the brain and in the spinal column. These receptors are located at the end of dendrites on a neurone cell. The dendrites send messages to other neurones through these, but when a drug that blocks the NMDA activity is taken, they are partially or entirely blocked, decreasing the brain's ability to transfer information across itself. Disconnecting the neurones and causing feelings of extreme dissociation or detachment, leading to hallucinatory states. Causing states of moderate to extreme dissociation in the user as the subconscious brain begins to fill in these sensory gaps with entirely imagined hallucinations and dreamlike states.

	==Common Dissociatives==		==Common Dissociatives==

Sleep at 00:51, 4 June 2018

2018-06-04T00:51:00Z

Show changes

Etherbinge79: Made the name for Diethyl Ether longer

2018-03-26T08:38:27Z

Made the name for Diethyl Ether longer

← Older revision		Revision as of 03:38, 26 March 2018
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	* [[Nitrous]]		* [[Nitrous]]
	* [[Diphenidine]]		* [[Diphenidine]]
	* [[Ether]]		* [[Diethyl Ether]]

	==Effects==		==Effects==

Etherbinge79: I believe that there should be a page made for Diethyl Ether as it is a dissociative anesthetic that is often inhaled in a dangerous manner since it is often not pure diethyl ether but extracted. There is some harm reduction that can be performed here.

2018-03-26T08:25:01Z

I believe that there should be a page made for Diethyl Ether as it is a dissociative anesthetic that is often inhaled in a dangerous manner since it is often not pure diethyl ether but extracted. There is some harm reduction that can be performed here.

← Older revision		Revision as of 03:25, 26 March 2018
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	* [[Nitrous]]		* [[Nitrous]]
	* [[Diphenidine]]		* [[Diphenidine]]
			* [[Ether]]

	==Effects==		==Effects==

Sleep: Getting better all the time...

2017-05-26T05:36:32Z

Getting better all the time...

Show changes

Reality: /* Effects */

2015-05-24T20:57:53Z

Effects

← Older revision		Revision as of 15:57, 24 May 2015
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	States of dissociation and detachment increase proportionally to dosage until they become completely detached from the external environment and eventually their own bodies causing them to slip into the famous dissociative hole.		States of dissociation and detachment increase proportionally to dosage until they become completely detached from the external environment and eventually their own bodies causing them to slip into the famous dissociative hole.

	A process which can be broken down into 4 distinct levels of increasing intensity.		A process which can be broken down into three distinct levels of increasing intensity.

	1. '''Partial detachment'''		1. '''Partial detachment'''

GrimReaper at 09:31, 13 March 2015

2015-03-13T09:31:08Z

← Older revision		Revision as of 04:31, 13 March 2015
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	==Links==		==Links==
	http://en.wikipedia.org/wiki/Dissociative		http://en.wikipedia.org/wiki/Dissociative

	~~[[Category:Dissociative]]~~

	==References==		==References==

	<references />		<references />

			[[Category:Drug class]]