Benzodiazepines - Revision history

Gaius: /* Dosage */

2018-07-08T00:15:17Z

Dosage

← Older revision		Revision as of 19:15, 7 July 2018
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	\| Anxiolytic		\| Anxiolytic
	\|-		\|-
	\| Clonazolam		\| [[Clonazolam]]
	\| N/A		\| N/A
	\| 0.2 mg		\| 0.2 mg

Gaius: /* Chemistry and Pharmacology */

2018-07-07T23:34:17Z

Chemistry and Pharmacology

← Older revision		Revision as of 18:34, 7 July 2018
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	::Clonazepam, Flunitrazepam, Nimetazepam, Nitrazepam		::Clonazepam, Flunitrazepam, Nimetazepam, Nitrazepam
	* Triazolo compounds:		* Triazolo compounds:
	::Adinazolam, Alprazolam, Estazolam, Triazolam		::Adinazolam, Alprazolam, Clonazolam, Estazolam, Triazolam
	* Imidazo compounds		* Imidazo compounds
	::Climazolam, Loprazolam, Midazolam		::Climazolam, Loprazolam, Midazolam

Gaius: Added Clonazolam

2018-07-07T23:23:39Z

Added Clonazolam

← Older revision		Revision as of 18:23, 7 July 2018
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	\| 18 - 50 hours		\| 18 - 50 hours
	\| 0.5 mg		\| 0.5 mg
			\| Anxiolytic
			\|-
			\| Clonazolam
			\| N/A
			\| 0.2 mg
	\| Anxiolytic		\| Anxiolytic
	\|-		\|-

Sleep: Now I recall why I hate myself.

2018-02-01T16:47:53Z

Now I recall why I hate myself.

← Older revision		Revision as of 11:47, 1 February 2018
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	\| Midazolam (Dormicum)		\| Midazolam (Dormicum)
	\| 1.6 - 8.3 hours		\| 1.6 - 8.3 hours
	\| ~~3.34mg~~		\| 10mg
	\| Hypnotic		\| Hypnotic
	\|-		\|-

Sleep: How the fuck can't I spell.

2018-02-01T13:55:33Z

How the fuck can't I spell.

← Older revision		Revision as of 08:55, 1 February 2018
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	\| Hypnotic		\| Hypnotic
	\|-		\|-
	\| ~~Chlordazepoxide~~ (Librium)		\| Chlordiazepoxide (Librium)
	\| 5 - 30 hours [36 - 200 hours]		\| 5 - 30 hours [36 - 200 hours]
	\| 25 mg		\| 25 mg

Sleep: Did things.

2017-11-07T05:19:00Z

Did things.

← Older revision		Revision as of 00:19, 7 November 2017
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	* High addiction potential		* High addiction potential
	* ~~Withdrawls~~ can be fatal		* Withdrawals can be fatal
	* Risk of blackout		* Risk of blackout
	* Inability to drink		* Inability to drink
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	* Procrastination		* Procrastination
	* "Hangover"		* "Hangover"
	* Long term effects		* Long-term effects
	* High addiction potential		* High addiction potential

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	The main danger of the drugs in this class is the risk of blacking out or overdosing by mixing it with other CNS depressants.		The main danger of the drugs in this class is the risk of blacking out or overdosing by mixing it with other CNS depressants.

	Most of the research chemicals from this class are usually active under 10mg's. The best course of action with these substances is putting X amount of active chemical into X amount of your solvent of choice (Such as Propylene-Glycol or Ethanol) And using an oral syringe to get the dose you want. Granted a fair amount are sold are either in presses or on blotter.		Most of the research chemicals from this class are usually active under 10mg's. The best course of action with these substances is putting X amount of active chemical into X amount of your solvent of choice (Such as Propylene-Glycol or Ethanol) And using an oral syringe to get the dose you want. Granted a fair amount are sold are either in presses or on a blotter.

	See the [[Research Chemicals]] page for more information.		See the [[Research Chemicals]] page for more information.
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	The term benzodiazepine is the chemical name for the heterocyclic ring system, which is a fusion between the benzene and diazepine ring systems. Under Hantzsch–Widman nomenclature, a diazepine is a heterocycle with two nitrogen atoms, five carbon atom and the maximum possible number of cumulative double bonds. The "benzo" prefix indicates the benzene ring fused onto the diazepine ring.		The term benzodiazepine is the chemical name for the heterocyclic ring system, which is a fusion between the benzene and diazepine ring systems. Under Hantzsch–Widman nomenclature, a diazepine is a heterocycle with two nitrogen atoms, five carbon atom and the maximum possible number of cumulative double bonds. The "benzo" prefix indicates the benzene ring fused onto the diazepine ring.
	Benzodiazepine drugs are substituted 1,4-benzodiazepines, although the chemical term can refer to many other compounds that do not have useful pharmacological properties. Different benzodiazepine drugs have different side groups attached to this central structure. The different side groups affect the binding of the molecule to the GABAA receptor and so modulate the pharmacological properties. Many of the pharmacologically active "classical" benzodiazepine drugs contain the 5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one substructure.		Benzodiazepine drugs are substituted 1,4-benzodiazepines, although the chemical term can refer to many other compounds that do not have useful pharmacological properties. Different benzodiazepine drugs have different side groups attached to this central structure. The different side groups affect the binding of the molecule to the GABAA receptor and so modulate the pharmacological properties. Many of the pharmacologically active "classical" benzodiazepine drugs contain the 5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one substructure.
	Nonbenzodiazepines also bind to the benzodiazepine binding site on the GABA(A) receptor and possess similar pharmacological properties. While the nonbenzodiazepines are by definition structurally unrelated to the benzodiazepines, both classes of drugs possess a common pharmacophore , which explains their binding to a common receptor site		Nonbenzodiazepines also bind to the benzodiazepine binding site on the GABA(A) receptor and possess similar pharmacological properties. While the nonbenzodiazepines are by definition structurally unrelated to the benzodiazepines, both classes of drugs possess a common pharmacophore, which explains their binding to a common receptor site

	[[File:benzo.png\|500px]]		[[File:benzo.png\|500px]]

Sleep: Added sortable to the Z-drugs.

2017-04-09T03:32:00Z

Added sortable to the Z-drugs.

← Older revision		Revision as of 22:32, 8 April 2017
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	\|}		\|}

	{\| class="wikitable"		{\| class="wikitable sortable"
	\|+Non-benzodiazepines commonly referred to as Z-drugs		\|+Non-benzodiazepines commonly referred to as Z-drugs
	! Chemical name (brand name)		! Chemical name (brand name)

Sleep: Missed a hyperlink.

2017-03-01T05:37:26Z

Missed a hyperlink.

← Older revision		Revision as of 00:37, 1 March 2017
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	\| Hypnotic		\| Hypnotic
	\|-		\|-
	\| [[Etizolam\|Etizolam]] (Etilaam, Etizola, Etizest, Depas)		\| [[Etizolam\|Etizolam (Etilaam, Etizola, Etizest, Depas)]]
	\| 4-12 hours		\| 4-12 hours
	\| 1mg		\| 1mg

Sleep at 05:36, 1 March 2017

2017-03-01T05:36:23Z

← Older revision		Revision as of 00:36, 1 March 2017
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	\| Anxiolytic		\| Anxiolytic
	\|-		\|-
	\| Diclazepam (Ro5-3448~~, 2'Chlorodiazepam~~)		\| Diclazepam (Ro5-3448)
	\| ~42 hours		\| ~42 hours
	\| 1mg		\| 1mg

Sleep: Added some brand names.

2017-03-01T05:35:50Z

Added some brand names.

← Older revision		Revision as of 00:35, 1 March 2017
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	\| Anxiolytic		\| Anxiolytic
	\|-		\|-
	\| Brotizolam		\| Brotizolam (Lendormin)
	\| 2 - 6 hours		\| 2 - 6 hours
	\| .25mg		\| .25mg
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	\| Anxiolytic		\| Anxiolytic
	\|-		\|-
	\| Diclazepam		\| Diclazepam (Ro5-3448, 2'Chlorodiazepam)
	\| ~42 hours		\| ~42 hours
	\| 1mg		\| 1mg
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	\| Hypnotic		\| Hypnotic
	\|-		\|-
	\| [[Etizolam\|Etizolam]]		\| [[Etizolam\|Etizolam]] (Etilaam, Etizola, Etizest, Depas)
	\| 4-12 hours		\| 4-12 hours
	\| 1mg		\| 1mg