5-MeO-DMT - Revision history

GrimReaper: /* Effects */

2015-04-03T17:52:08Z

Effects

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	== Effects ==		== Effects ==

	=== Postive ===		=== Postive ===

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	*Occasional euphoria		*Occasional euphoria
	*Sensual enhancement		*Sensual enhancement


	=== Neutral ===		=== Neutral ===
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	*Dissociation		*Dissociation
	*Muscle jerking		*Muscle jerking


	=== Negative ===		=== Negative ===

GrimReaper at 17:51, 3 April 2015

2015-04-03T17:51:54Z

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	*Overly-intense experiences		*Overly-intense experiences
	*Hard on the lungs to smoke		*Hard on the lungs to smoke

	~~== Images ==~~
	~~<gallery>~~
	~~File:Example.jpg\| ''Example image 1''~~
	~~File:Example.jpg\| ''Example image with link: [[TripSit Rules]]''~~
	~~</gallery>~~


	== Harm Reduction ==		== Harm Reduction ==

GrimReaper at 17:51, 3 April 2015

2015-04-03T17:51:30Z

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	<!-- This is a basic drug template. Feel free to copy/paste it in new articles -->		<!-- This is a basic drug template. Feel free to copy/paste it in new articles -->
	[[File:~~Example~~.jpg~~\|thumb~~\|250px\|right]]		[[File:Bufo-alvarius.jpg\|250px\|right]]
	'''5-MeO-DMT''' was first discovered in ''Dictyoloma incanescens'' and later was isolated from ''Anadenanthera peregrina'' as well. It occurs in a very large number of plants, often in association with [[N,N-DMT]]. Its effects are somewhat more potent than those of N,N-DMT. When the two are administered simultaneously, 5-MeO-DMT more quickly occupies the specific receptors. 5-MeO-DMT is a natural neurotransmitter in the human nervous system. When 5-MeO-DMT (10 to 20 mg) is smoked or vaporized and inhaled, the effects are almost immediately apparent, are incredibly extreme, and last about ten minutes. Many people report having shamanic experiences with this substance as well as experiencing states of enlightenment and the clear light of nirvana (Metzner 1988). The Colorado River toad (''Bufo alvarius'') is native to the area around Tucson, Arizona. These toads spend nine months of the year underground, buried in the mud that keeps them protected from the burning desert sun. The toads emerge from their hiding places with the first rains and begin their courtship (Smith 1982,97-100). They remain visible for only three months. Like all toads, Bufo alvarius develops mucous secretions in two glands that are located on the neck The secretions of the Colorado River toad, however, do not contain bufotoxine, the toxic substance that is found in the secretions of most other toads. Instead, the dried mass contains 15% 5-MeO-DMT (Erspamer et al. 1965, 1967). The native tribes that lived in the North American Southwest made fetishes of this Bufo alvarius. However, it was only in recent times that the toad's cultural importance and its psychedelic use were discovered, or more likely rediscovered (cf. Davis and Weil 1992). The toad is "milked" by being held firmly without being crushed. Both glands are then massaged gently until a fat stream of the secretion squirts out. The secretion is caught on a piece of glass, where it is allowed to dry and crystallize. The yellowish crystalline mass then can be scraped off, mixed with different herbs (such as damiana [Turnera diffusa] ), and smoked. The toad, which is released unharmed, is quickly able to replenish the loss in its secretions. When taken orally, Bufo alvarius secretions are apparently toxic, whereas they are not poisonous when smoked (Weil and Davis 1994). Davis and Weil have suggested that the dried secretions of Bufo alvarius were traded to Mexico in preColumbian times and that the priests and shamans there smoked or used it in some other manner (Davis and Weil1992; cf. balche', bufotenine). In Arizona, there is now a Church of the Toad of Light, which uses the secretions of Bufo alvarius as a sacrament (Most 1984; Ott 1993,396*).		'''5-MeO-DMT''' was first discovered in ''Dictyoloma incanescens'' and later was isolated from ''Anadenanthera peregrina'' as well. It occurs in a very large number of plants, often in association with [[N,N-DMT]]. Its effects are somewhat more potent than those of N,N-DMT. When the two are administered simultaneously, 5-MeO-DMT more quickly occupies the specific receptors. 5-MeO-DMT is a natural neurotransmitter in the human nervous system. When 5-MeO-DMT (10 to 20 mg) is smoked or vaporized and inhaled, the effects are almost immediately apparent, are incredibly extreme, and last about ten minutes. Many people report having shamanic experiences with this substance as well as experiencing states of enlightenment and the clear light of nirvana (Metzner 1988). The Colorado River toad (''Bufo alvarius'') is native to the area around Tucson, Arizona. These toads spend nine months of the year underground, buried in the mud that keeps them protected from the burning desert sun. The toads emerge from their hiding places with the first rains and begin their courtship (Smith 1982,97-100). They remain visible for only three months. Like all toads, Bufo alvarius develops mucous secretions in two glands that are located on the neck The secretions of the Colorado River toad, however, do not contain bufotoxine, the toxic substance that is found in the secretions of most other toads. Instead, the dried mass contains 15% 5-MeO-DMT (Erspamer et al. 1965, 1967). The native tribes that lived in the North American Southwest made fetishes of this Bufo alvarius. However, it was only in recent times that the toad's cultural importance and its psychedelic use were discovered, or more likely rediscovered (cf. Davis and Weil 1992). The toad is "milked" by being held firmly without being crushed. Both glands are then massaged gently until a fat stream of the secretion squirts out. The secretion is caught on a piece of glass, where it is allowed to dry and crystallize. The yellowish crystalline mass then can be scraped off, mixed with different herbs (such as damiana [Turnera diffusa] ), and smoked. The toad, which is released unharmed, is quickly able to replenish the loss in its secretions. When taken orally, Bufo alvarius secretions are apparently toxic, whereas they are not poisonous when smoked (Weil and Davis 1994). Davis and Weil have suggested that the dried secretions of Bufo alvarius were traded to Mexico in preColumbian times and that the priests and shamans there smoked or used it in some other manner (Davis and Weil1992; cf. balche', bufotenine). In Arizona, there is now a Church of the Toad of Light, which uses the secretions of Bufo alvarius as a sacrament (Most 1984; Ott 1993,396*).

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Sleep at 20:37, 23 December 2014

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			[[Category:Research Chemical]]

GrimReaper at 15:37, 14 July 2014

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		[[Category:Drugs]]
		[[Category:Psychedelic]]

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Roi: Roi moved page 5-MEO-DMT to 5-MeO-DMT

2014-03-17T13:08:49Z

Roi moved page 5-MEO-DMT to 5-MeO-DMT

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Reality at 13:00, 27 February 2014

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			[[Category:Drugs]]
			[[Category:Psychedelic]]

205.56.181.196: Created page with "

..."
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Created page with " <table style="font-family: Arial, Helvetica, sans-serif; font-size: 9pt;" width="100%" border="0" cellspacing="0" cellpadding="0"> <tr> <td valign="top" width="50%"><strong>..."

New page

<table style="font-family: Arial, Helvetica, sans-serif; font-size: 9pt;" width="100%" border="0" cellspacing="0" cellpadding="0">

<tr>
<td valign="top" width="50%"><strong>Other Names</strong>

Dimethyl-5-methoxytryptamine, 5-methoxy-DMT,

5-methoxy-N,N-dimethyl-tryptamine, 0-methylbufotenine,

3- [2-(dimethylamino)ethyl] -5-methoxy-

indole, toad foam

Substance type: tryptamine (indole alkaloid)

5-MeO-DMT was first discovered in Dictyoloma

incanescens DC. and later was isolated from Anadenanthera

peregrina as well. It occurs in a very

large number of plants, often in association with

N,N-DMT (see the table on pages 853-854). Its

effects are somewhat more potent than those of

N,N-DMT. When the two are administered simultaneously,

5-MeO-DMT more quickly occupies

the specific receptors. 5-MeO-DMT is a natural

neurotransmitter in the human nervous system.

When 5-MeO-DMT (10 to 20 mg) is smoked or

vaporized and inhaled, the effects are almost

immediately apparent, are incredibly extreme, and

last about ten minutes. Many people report having

shamanic experiences with this substance as well

as experiencing states of enlightenment and the

clear light of nirvana (Metzner 1988).

The Colorado River toad (Bufo alvarius) is

native to the area around Tucson, Arizona. These

toads spend nine months of the year underground,

buried in the mud that keeps them protected from

the burning desert sun. The toads emerge from

their hiding places with the first rains and begin

their courtship (Smith 1982,97-100). They remain

visible for only three months. Like all toads, Bufo

alvarius develops mucous secretions in two glands

that are located on the neck The secretions of the

Colorado River toad, however, do not contain

bufotoxine, the toxic substance that is found in the

secretions of most other toads. Instead, the dried

mass contains 15% 5-MeO-DMT (Erspamer et al.

1965, 1967).

The native tribes that lived in the North

American Southwest made fetishes of this Bufo

alvarius. However, it was only in recent times that

the toad's cultural importance and its psychedelic

use were discovered, or more likely rediscovered

(cf. Davis and Weil 1992). The toad is "milked" by

being held firmly without being crushed. Both

glands are then massaged gently until a fat stream

of the secretion squirts out. The secretion is

caught on a piece of glass, where it is allowed to

dry and crystallize. The yellowish crystalline mass

then can be scraped off, mixed with different herbs

(such as damiana [Turnera diffusa] ), and smoked.

The toad, which is released unharmed, is quickly

able to replenish the loss in its secretions.

When taken orally, Bufo alvarius secretions are

apparently toxic, whereas they are not poisonous

when smoked (Wei! and Davis 1994). Davis and

Weil have suggested that the dried secretions of

Bufo alvarius were traded to Mexico in preColumbian

times and that the priests and shamans

there smoked or used it in some other manner

(Davis and Weil1992; cf. balche', bufotenine).

In Arizona, there is now a Church of the Toad

of Light, which uses the secretions of Bufo alvarius

as a sacrament (Most 1984; Ott 1993,396*).</td>
<td valign="top" width="53%"><strong>Commercial Forms and Regulations</strong>

Pure 5-MeO-DMT is available from chemical

suppliers. While the substance is not explicitly

mentioned in the narcotics laws, the fact that it

could be interpreted as a DMT analog may result

in problems with the law.

<strong>Literature</strong>

See also the entries for bufotenine.

Davis, Wade, and Andrew T. Wei!. 1992. Identity of a

New World psychoactive toad. Ancient

Mesoamerica 3:51-59.

Erspamer, v., T. Vitali, M. Roseghini, and J. M. Cei.

1965. 5-methoxy and 5-hydroxyindolalkylamines

in the skin of Bufo alvarius.

Experientia 21:504.

---.1967. 5-methoxy- and 5-hydroxyindoles in

the skin of Bufo alvarius. Biochemical

Pharmacology 16:1149-64.

Metzner, Ralph. 1988. Hallucinogens in

contemporary North American shamanic

practice. In Proceedings ofthe Fourth

International Conference on the Study of

Shamanism and Alternate Modes ofHealing

(Independent Scholars of Asia), 170-75.

Most, A. 1984. Bufo alvarius: The psychedelic toad of

the Sonoran Desert. Denton, Texas: Venom Press.

Witsch, Christian. 1993. Die Krbtenmutter. In

Naturverehrung und Heilkunst, ed. C. R~itsch,

125-28. Sudergellersen: Bruno Martin.

Smith, Robert 1. 1982. Venomous animals ofArizona.

Bulletin 8245. Tucson: The University of Arizona.

Weil, Andrew T., and Wade Davis. 1994. Bufo

alvarius: A potent hallucinogen of animal origin.

Journal ofEthnopharmacology 41: 1-8.</td>
</tr>

</table>