2C-D - Revision history

Sleep at 02:04, 18 October 2016

2016-10-18T02:04:23Z

← Older revision		Revision as of 21:04, 17 October 2016
Line 73:		Line 73:
	*Other names: 2,5-Dimethoxy-4-methyl-phenthylamine		*Other names: 2,5-Dimethoxy-4-methyl-phenthylamine
	*CAS# 25505-65-1		*CAS# 25505-65-1

			=== Pharmacology ===
			Like most psychedelic drugs, 2C-D is a 5-HT2a Agonist; from that, we can presume the concurrent or pre-administration of SSRIs may reduce the effects of 2C-D. The 2C-X family, specifically, 2C-E, 2C-I, and 2C-C all stimulated G protein binding, suggesting more of an activity similar to tryptamines such as 5-MeO-DMT and, interestingly, DPT. G Proteins are membrane proteins that effectively mediate interaction between hormone receptors and enzymes responsible for changes of metabolism as a result of hormonal changes.

			In rats, Stage I metabolism involved deamination and O-Demthylation, which are related to the Monoamine oxidase (MAO) and cytochrome P450 (CYP) enzymes. For virtually all the 2C’s, (B,I,D,E,T-2, and T-7), MAO-A and MAO-B were reacted upon; interestingly, ½ of the molecules in Shulgin’s Magical Half Dozen (2C-E, 2C-T-2, 2C-T-7, with the addition of 2C-D) also act to a small extent on the CYP2D6 enzyme. Because of the commonality of these receptors, the 2C-X family is likely to be more reactive with other concurrently administered chemicals.

	== Harm Reduction ==		== Harm Reduction ==

Dread at 17:26, 19 September 2016

2016-09-19T17:26:29Z

← Older revision		Revision as of 12:26, 19 September 2016
Line 10:		Line 10:
	== Dosage ==		== Dosage ==

			{{#tdose: 2cd }}
	{~~\| class="wikitable"~~
	~~\|+ Oral~~
	\|-
	~~\| Threshold \|\| 3-4 mg~~
	\|-
	~~\| Light \|\| 5-15mg~~
	\|-
	~~\| Common \|\| 20-50mg~~
	\|-
	~~\| Strong \|\| 50-100mg~~
	\|}

	== Duration ==		== Duration ==

Sleep: Added tables.

2016-06-18T15:36:57Z

Added tables.

← Older revision		Revision as of 10:36, 18 June 2016
Line 10:		Line 10:
	== Dosage ==		== Dosage ==

	*Oral

	*Threshold: 3-~~4mg~~		{\| class="wikitable"
			\|+ Oral
	*Light: 5-15mg		\|-
			\| Threshold \|\| 3-4 mg
	*Commom:20-50mg		\|-
			\| Light \|\| 5-15mg
	*Strong: 50-100mg+		\|-
			\| Common \|\| 20-50mg
			\|-
			\| Strong \|\| 50-100mg
			\|}

	== Duration ==		== Duration ==

	*Oral		{\| class="wikitable"
			\|+ Oral
	*Onset: 15-45 minutes		\|-
	*Total ~~duration:~~ 3-5 hours		\| Onset \|\|15-45 minutes.
			\|-
			\| Total \|\| 3-5 hours.
			\|}

	== Effects ==		== Effects ==

GrimReaper at 09:02, 10 March 2015

2015-03-10T09:02:30Z

← Older revision		Revision as of 04:02, 10 March 2015
Line 19:		Line 19:

	*Strong: 50-100mg+		*Strong: 50-100mg+


	== Duration ==		== Duration ==


	*Oral		*Oral
Line 28:		Line 26:
	*Onset: 15-45 minutes		*Onset: 15-45 minutes
	*Total duration: 3-5 hours		*Total duration: 3-5 hours


	== Effects ==		== Effects ==

GrimReaper at 09:02, 10 March 2015

2015-03-10T09:02:08Z

← Older revision		Revision as of 04:02, 10 March 2015
Line 1:		Line 1:
	[[File:--File-2C-D.gif\|thumb\|right]]		[[File:--File-2C-D.gif\|thumb\|right]]

	~~= General Information =~~		'''2C-D''' is a short acting psychedelic drug of the [[2C-X\|2C-X family]].

	2C-D is a short acting psychedelic drug of the [[2C-X\|2C-X family]].
	The effects of 2C-D are usually compared to 2C-B (although not as visual as 2C-B) or other psychedelic stimulants and sometimes to MDMA (ecstasy). Its effects are generally considered milder than 2C-B, LSD, or MDMA. 2C-D is also known for the strong body component of its effects which are alternately described as pleasurable energy or a 'sense of being in the body', and by others as an unpleasant 'buzzing' or body-load, which is mostly occurring during onset.		The effects of 2C-D are usually compared to 2C-B (although not as visual as 2C-B) or other psychedelic stimulants and sometimes to MDMA (ecstasy). Its effects are generally considered milder than 2C-B, LSD, or MDMA. 2C-D is also known for the strong body component of its effects which are alternately described as pleasurable energy or a 'sense of being in the body', and by others as an unpleasant 'buzzing' or body-load, which is mostly occurring during onset.
	Shulgin himself referred to this substance as a “pharmacological tofu,” meaning that when mixed with other substances, it can extend or potentiate their effects without coloring the experience too much, in a manner similar to how tofu absorbs the flavors of sauces or spices it is cooked with. Some people have claimed 2C-D is relatively uninteresting on its own, but many other users have strongly disagreed with this assessment and believe instead 2C-D to be a true psychedelic in its own right.		Shulgin himself referred to this substance as a “pharmacological tofu,” meaning that when mixed with other substances, it can extend or potentiate their effects without coloring the experience too much, in a manner similar to how tofu absorbs the flavors of sauces or spices it is cooked with. Some people have claimed 2C-D is relatively uninteresting on its own, but many other users have strongly disagreed with this assessment and believe instead 2C-D to be a true psychedelic in its own right.

	= History =		== History ==
	It was first synthesized in 1970 by a team from the Texas Research Institute of Mental Sciences, and its activity was subsequently investigated in humans by Alexander Shulgin.		It was first synthesized in 1970 by a team from the Texas Research Institute of Mental Sciences, and its activity was subsequently investigated in humans by Alexander Shulgin.

	= Dosage =		== Dosage ==

	*Oral		*Oral
Line 23:		Line 21:


	= Duration =		== Duration ==


Line 32:		Line 30:


	= Effects =		== Effects ==
	== Positive ==		=== Positive ===

	* Euphoria		* Euphoria
Line 51:		Line 49:
	* Spontaneity		* Spontaneity

	== Neutral ==		=== Neutral ===

	* Decreased Appetite		* Decreased Appetite
Line 61:		Line 59:
	* Mild elevation in heart rate		* Mild elevation in heart rate

	== Negative ==		=== Negative ===

	* Restlessness		* Restlessness
Line 79:		Line 77:
	* Anxiety		* Anxiety

	= Chemistry and Pharmacology =		== Chemistry and Pharmacology ==
	*IUPAC: 1-(2,5-Dimethoxy-4-Methylphenyl)-2-aminoethane		*IUPAC: 1-(2,5-Dimethoxy-4-Methylphenyl)-2-aminoethane
	*Other names: 2,5-Dimethoxy-4-methyl-phenthylamine		*Other names: 2,5-Dimethoxy-4-methyl-phenthylamine
	*CAS# 25505-65-1		*CAS# 25505-65-1

	= Harm Reduction =		== Harm Reduction ==

	2C-D is one of the safer psychedelics, with several reported cases of users far exceeding commonly used dosing limits without lasting adverse physical effects. It is also observed to have a low addiction potential. It is a stimulating psychedelic, and therefore it's important to remain hydrated. Refer to [[Psychedelics#Harm_Reduction\|Psychedelic Harm Reduction]] for more information.		2C-D is one of the safer psychedelics, with several reported cases of users far exceeding commonly used dosing limits without lasting adverse physical effects. It is also observed to have a low addiction potential. It is a stimulating psychedelic, and therefore it's important to remain hydrated. Refer to [[Psychedelics#Harm_Reduction\|Psychedelic Harm Reduction]] for more information.

	= Legal Status =		== Legal Status ==

	* Denmark: 2C-D is added to the list of Schedule B controlled substances.		* Denmark: 2C-D is added to the list of Schedule B controlled substances.
Line 96:		Line 94:
	* United States: [http://www.justice.gov/dea/druginfo/ds.shtml Schedule I] (Illegal to produce, supply, or possess)		* United States: [http://www.justice.gov/dea/druginfo/ds.shtml Schedule I] (Illegal to produce, supply, or possess)

	= Links =		== Links ==

	[https://en.wikipedia.org/wiki/2C-D Wikipedia]		[https://en.wikipedia.org/wiki/2C-D Wikipedia]

Sleep at 20:17, 23 December 2014

2014-12-23T20:17:15Z

← Older revision		Revision as of 15:17, 23 December 2014
Line 106:		Line 106:
	[[Category:Drugs]]		[[Category:Drugs]]
	[[Category:Psychedelic]]		[[Category:Psychedelic]]
			[[Category:Research Chemical]]

Sleep: Cleaning up.

2014-08-01T18:50:47Z

Cleaning up.

← Older revision		Revision as of 13:50, 1 August 2014
Line 1:		Line 1:
	[[File:--File-2C-D.gif\|thumb\|right]]		[[File:--File-2C-D.gif\|thumb\|right]]
	~~'''~~2C-D~~'''~~ is a short acting psychedelic drug of the [[2C-X\|2C-X family]].
			= General Information =

			2C-D is a short acting psychedelic drug of the [[2C-X\|2C-X family]].
	The effects of 2C-D are usually compared to 2C-B (although not as visual as 2C-B) or other psychedelic stimulants and sometimes to MDMA (ecstasy). Its effects are generally considered milder than 2C-B, LSD, or MDMA. 2C-D is also known for the strong body component of its effects which are alternately described as pleasurable energy or a 'sense of being in the body', and by others as an unpleasant 'buzzing' or body-load, which is mostly occurring during onset.		The effects of 2C-D are usually compared to 2C-B (although not as visual as 2C-B) or other psychedelic stimulants and sometimes to MDMA (ecstasy). Its effects are generally considered milder than 2C-B, LSD, or MDMA. 2C-D is also known for the strong body component of its effects which are alternately described as pleasurable energy or a 'sense of being in the body', and by others as an unpleasant 'buzzing' or body-load, which is mostly occurring during onset.
	Shulgin himself referred to this substance as a “pharmacological tofu,” meaning that when mixed with other substances, it can extend or potentiate their effects without coloring the experience too much, in a manner similar to how tofu absorbs the flavors of sauces or spices it is cooked with. Some people have claimed 2C-D is relatively uninteresting on its own, but many other users have strongly disagreed with this assessment and believe instead 2C-D to be a true psychedelic in its own right.		Shulgin himself referred to this substance as a “pharmacological tofu,” meaning that when mixed with other substances, it can extend or potentiate their effects without coloring the experience too much, in a manner similar to how tofu absorbs the flavors of sauces or spices it is cooked with. Some people have claimed 2C-D is relatively uninteresting on its own, but many other users have strongly disagreed with this assessment and believe instead 2C-D to be a true psychedelic in its own right.
Line 8:		Line 11:

	= Dosage =		= Dosage =
	~~'''NOTE: DO NOT TAKE THE BELOW DOSING INFORMATION AS A KNOW ALL, PLEASE TAKE CAUTION, AND REMEMBER THAT YOU CAN ALWAYS TAKE MORE, BUT NEVER LESS.'''~~

	~~{\| class="wikitable"~~		*Oral
	\|+ Oral
	\|-		*Threshold: 3-4mg
	\| Threshold \|\| 3-4mg
	\|-		*Light: 5-15mg
	\| Light \|\| 5-15mg
	\|-		*Commom:20-50mg
	~~\| Common \|\|~~ 20-50mg
	\|-		*Strong: 50-100mg+
	\| Strong \|\| 50-100mg
	\|}

	= Duration =		= Duration =

	~~{\| class="wikitable"~~
	\|+ Oral		*Oral
	\|-
	\| Onset \|\| 15-45 minutes		*Onset: 15-45 minutes
	\|-		*Total duration: 3-5 hours
	\| Total \|\| 3-5 hours
	\|}

	= Effects =		= Effects =

Roi at 11:08, 1 August 2014

2014-08-01T11:08:43Z

← Older revision		Revision as of 06:08, 1 August 2014
Line 1:		Line 1:
			[[File:--File-2C-D.gif\|thumb\|right]]
	'''2C-D''' is a short acting psychedelic drug of the [[2C-X\|2C-X family]].		'''2C-D''' is a short acting psychedelic drug of the [[2C-X\|2C-X family]].
	The effects of 2C-D are usually compared to 2C-B (although not as visual as 2C-B) or other psychedelic stimulants and sometimes to MDMA (ecstasy). Its effects are generally considered milder than 2C-B, LSD, or MDMA. 2C-D is also known for the strong body component of its effects which are alternately described as pleasurable energy or a 'sense of being in the body', and by others as an unpleasant 'buzzing' or body-load, which is mostly occurring during onset.		The effects of 2C-D are usually compared to 2C-B (although not as visual as 2C-B) or other psychedelic stimulants and sometimes to MDMA (ecstasy). Its effects are generally considered milder than 2C-B, LSD, or MDMA. 2C-D is also known for the strong body component of its effects which are alternately described as pleasurable energy or a 'sense of being in the body', and by others as an unpleasant 'buzzing' or body-load, which is mostly occurring during onset.

Sleep: /* Chemistry and Pharmacology */

2014-08-01T10:44:05Z

Chemistry and Pharmacology

← Older revision		Revision as of 05:44, 1 August 2014
Line 80:		Line 80:

	= Chemistry and Pharmacology =		= Chemistry and Pharmacology =
	IUPAC: 1-(2,5-Dimethoxy-4-Methylphenyl)-2-aminoethane		*IUPAC: 1-(2,5-Dimethoxy-4-Methylphenyl)-2-aminoethane
	Other names: 2,5-Dimethoxy-4-methyl-phenthylamine		*Other names: 2,5-Dimethoxy-4-methyl-phenthylamine
	CAS# 25505-65-1		*CAS# 25505-65-1

	= Harm Reduction =		= Harm Reduction =

Sleep: /* Chemistry and Pharmacology */

2014-08-01T10:42:49Z

Chemistry and Pharmacology

← Older revision		Revision as of 05:42, 1 August 2014
Line 80:		Line 80:

	= Chemistry and Pharmacology =		= Chemistry and Pharmacology =
	~~Systematic name~~: 2,5-~~dimethoxy~~-4-~~methylphenethylamine~~		IUPAC: 1-(2,5-Dimethoxy-4-Methylphenyl)-2-aminoethane
			Other names: 2,5-Dimethoxy-4-methyl-phenthylamine
			CAS# 25505-65-1

	= Harm Reduction =		= Harm Reduction =