TripSit Wiki - User contributions [en]

Scopolamine

2023-01-16T06:56:57Z

Llarpiwhal: /* Dosage */

Scopolamine, also known as hyoscine, is a tropane alkaloid found in various nightshade plants, including Belladonna and Datura. Historically, it has been used as a poison in some cultures and is also used as a medication for motion sickness. Scopolamine is toxic at recreational doses. Use can lead to memory impairment and cognitive dysfunction.

=== Dosage ===
Scopolamine should not be taken in its plant form as the potency can vary greatly. The recreational dose, if any, is not well established. The recommended therapeutic dose is usually 0.2mg to 0.4mg, and it should only be taken under medical supervision. Another form of Scopolamine, butylscopolamine, can be found in smoked Buscopan tablets, however, a safe recreational dose has not been established.

=== Duration ===
{|
|-
| Onset || 20-120 minutes
| Total || 3-24+ hours
|}

=== Effects ===
===== Positive =====
* Euphoria

===== Neutral =====
*Pupil dilation
*Blurred vision
*Sedation

===== Negative =====
*Delirium
*Tachycardia
*Irregular heartbeat
*Nausea
*Urinary retention
*Abnormal breathing
*Dry mouth
*Anxiety/Panic
*Confusion
*Memory loss
*Skin reddening
*Increased body temperature
===== After Effects =====
People have reported being unable to read fine text shortly after using scopolamine.

=== Harm Reduction ===
Physostigmine has been used to treat the effects of scopolamine.
Scopolamine should not be mixed with other anticholinergics, alcohol, zolpidem, or stimulants.
Due to the delirium caused by scopolamine, it shouldn't be used in combination with other hallucinogens.
For the same reason, It's important to have a trip sitter present when taking Scopolamine, as the user may not be able to distinguish reality from hallucinations.

=== Pharmacology ===
Scopolamine acts as an antimuscarinic at the m1 receptor. It works by inhibiting the activity of acetylcholine, which leads to the symptoms associated with Scopolamine toxicity. It also blocks the cholinergic receptors in the hippocampus.

=== Links ===
*[https://erowid.org/chemicals/scopolamine/scopolamine.shtml Erowid]
*[https://psychonautwiki.org/wiki/Datura#Pharmacology PsychonautWiki]
*[https://en.wikipedia.org/wiki/Hyoscine#Mechanism_of_action Wikipedia]

[[Category:Drugs]]
[[Category:Deliriant]]

Scopolamine

2023-01-16T06:54:38Z

Llarpiwhal: /* Dosage */

Scopolamine, also known as hyoscine, is a tropane alkaloid found in various nightshade plants, including Belladonna and Datura. Historically, it has been used as a poison in some cultures and is also used as a medication for motion sickness. Scopolamine is toxic at recreational doses. Use can lead to memory impairment and cognitive dysfunction.

=== Dosage ===
Scopolamine should not be taken in its plant form as the potency can vary greatly. The recreational dose, if any, is not well established. Another form of Scopolamine, butylscopolamine, can be found in smoked Buscopan tablets, however, a safe recreational dose has not been established.

=== Duration ===
{|
|-
| Onset || 20-120 minutes
| Total || 3-24+ hours
|}

=== Effects ===
===== Positive =====
* Euphoria

===== Neutral =====
*Pupil dilation
*Blurred vision
*Sedation

===== Negative =====
*Delirium
*Tachycardia
*Irregular heartbeat
*Nausea
*Urinary retention
*Abnormal breathing
*Dry mouth
*Anxiety/Panic
*Confusion
*Memory loss
*Skin reddening
*Increased body temperature
===== After Effects =====
People have reported being unable to read fine text shortly after using scopolamine.

=== Harm Reduction ===
Physostigmine has been used to treat the effects of scopolamine.
Scopolamine should not be mixed with other anticholinergics, alcohol, zolpidem, or stimulants.
Due to the delirium caused by scopolamine, it shouldn't be used in combination with other hallucinogens.
For the same reason, It's important to have a trip sitter present when taking Scopolamine, as the user may not be able to distinguish reality from hallucinations.

=== Pharmacology ===
Scopolamine acts as an antimuscarinic at the m1 receptor. It works by inhibiting the activity of acetylcholine, which leads to the symptoms associated with Scopolamine toxicity. It also blocks the cholinergic receptors in the hippocampus.

=== Links ===
*[https://erowid.org/chemicals/scopolamine/scopolamine.shtml Erowid]
*[https://psychonautwiki.org/wiki/Datura#Pharmacology PsychonautWiki]
*[https://en.wikipedia.org/wiki/Hyoscine#Mechanism_of_action Wikipedia]

[[Category:Drugs]]
[[Category:Deliriant]]

Scopolamine

2023-01-16T06:53:19Z

Llarpiwhal:

Scopolamine, also known as hyoscine, is a tropane alkaloid found in various nightshade plants, including Belladonna and Datura. Historically, it has been used as a poison in some cultures and is also used as a medication for motion sickness. Scopolamine is toxic at recreational doses. Use can lead to memory impairment and cognitive dysfunction.

=== Dosage ===
Scopolamine should not be taken in its plant form as the potency can vary greatly. The recreational dose, if any, is not well established and should not be exceeded unless under medical supervision. Another form of Scopolamine, butylscopolamine, can be found in smoked Buscopan tablets, however, a safe recreational dose has not been established.

=== Duration ===
{|
|-
| Onset || 20-120 minutes
| Total || 3-24+ hours
|}

=== Effects ===
===== Positive =====
* Euphoria

===== Neutral =====
*Pupil dilation
*Blurred vision
*Sedation

===== Negative =====
*Delirium
*Tachycardia
*Irregular heartbeat
*Nausea
*Urinary retention
*Abnormal breathing
*Dry mouth
*Anxiety/Panic
*Confusion
*Memory loss
*Skin reddening
*Increased body temperature
===== After Effects =====
People have reported being unable to read fine text shortly after using scopolamine.

=== Harm Reduction ===
Physostigmine has been used to treat the effects of scopolamine.
Scopolamine should not be mixed with other anticholinergics, alcohol, zolpidem, or stimulants.
Due to the delirium caused by scopolamine, it shouldn't be used in combination with other hallucinogens.
For the same reason, It's important to have a trip sitter present when taking Scopolamine, as the user may not be able to distinguish reality from hallucinations.

=== Pharmacology ===
Scopolamine acts as an antimuscarinic at the m1 receptor. It works by inhibiting the activity of acetylcholine, which leads to the symptoms associated with Scopolamine toxicity. It also blocks the cholinergic receptors in the hippocampus.

=== Links ===
*[https://erowid.org/chemicals/scopolamine/scopolamine.shtml Erowid]
*[https://psychonautwiki.org/wiki/Datura#Pharmacology PsychonautWiki]
*[https://en.wikipedia.org/wiki/Hyoscine#Mechanism_of_action Wikipedia]

[[Category:Drugs]]
[[Category:Deliriant]]

Salvia

2018-06-03T23:33:44Z

Llarpiwhal:

[[File:salvia.jpg|350px|right]]

'''Salvia Divinorum''' is a plant of the genus Salvia, which is psychoactive and known to induce intense and dysphoric hallucinatory experiences. It can either be smoked or taken sublingually, though the former is preferred by most users. Many of the users do not consider the drug to have much 'recreational' potential, due to the intense and often scary experience it yields - however it has seen value as a tool for spiritual use.

== History ==

The plant was originally endemic to the Sierra Madre mountains in Mexico, and has a long history of having been used by the Mazatecs for shamanic healing rituals - entering a shamanic state of consciousness using the substance to divine a patient's illness in the spirit world by integrating the plant into a tea preparation called "yerba de Maria."

The drug was first discovered in the Western world by R Gordon Wasson, a widely renowned botanist brought the plant back from Mexico as an object of scientific research - witnessing the plant being used in a similar manner to mushrooms in shamanic religious practice. It remained in relative obscurity until the 90s, at which time Western psychedelic exploration of the plant began.

Now, due to the Internet, the drug is widely available on the Internet and many users partake in the drug recreationally.

== Dosage ==

The doses for salvia vary wildly depending on the quality of the plant or extract. It is typically smoked in dried leaf form, while taken sublingually either as dried or fresh wet leaf. Salvia extracts are also commonly available, generally coming in 5x, 6x, 10x and even 20x concentrations - though the extraction process tends to lose a bit of the potency and therefore doses will not be accurately comparable with fresh product.

{| class="wikitable"
|+ Smoked
|-
| Threshold || 0.2g+
|-
| Common || 0.4g+
|-
| Heavy || 0.5g+
|}

{| class="wikitable"
|+ Sublingual (Wet Leaf)
|-
| Threshold || 10g+
|-
| Common || 30g+
|-
| Heavy || 50g+
|}

{| class="wikitable"
|+ Sublingual (Dried Leaf)
|-
| Threshold || 2g+
|-
| Common || 5g+
|-
| Heavy || 10g+
|}

== Duration ==

{| class="wikitable"
|+ All routes
|-
| Onset || 20-60 seconds
|-
| Total || 5-15 minutes
|-
| After-effects || 20-40 minutes
|}

== Effects ==

=== Postive ===

* Radical shift in perspective and perception

* Increase in sensual activity

* Introspective insight

* Powerful open/closed eye visuals

* Change in consciousness

=== Neutral ===

* Dissociation

* Perspiration

=== Negative ===

* Dysphoria

* Ataxia

* Dizziness

* Amnesia

* Nausea

== Harm Reduction ==

* Due to the ataxia and loss of body control, it is recommended to position yourself in a way that you will not aspirate during the experience (though vomiting from salvia is not a common occurrence).

* It is generally recommended to use a sitter while ingesting salvia, due to the mental intensity of the experience or potential for injury while in dysphoric state.

=== Potentiators ===

Users have reported an elongation and potentiation of the effects of the drug through using a [[MAOI]] such as Syrian Rue.

=== Interactions ===

== Chemistry and Pharmacology ==

The primary psychoactive constituent of salvia divinorum is a diterpenoid called salvinorin A, which is a potent k-opioid and d2 receptor agonist. Due to these properties, it has seen research indicating the drug may be of use as a treatment for opioid addiction - as well as providing research opportunities for the potential treatment of perception-altering diseases such as schizophrenia or Alzheimer's.

== Legal status ==

Salvia is legal in most countries, since its tendency to disable users and chemical safety mean that while users may not have a pleasant experience, it is very difficult to cause damage through physical or accidental means.

== Links ==

[https://en.wikipedia.org/wiki/Salvia_divinorum Wikipedia]

[https://www.erowid.org/plants/salvia/salvia.shtml Erowid]

[http://reddit.com/r/Drugs/comments/jkscw/rdrugs_ama_series_salvia_divinorum_salvia/?sort=top /r/Drugs FAQ]

[[Category:Drugs]]

[[Category:Dissociative]]

Scopolamine

2018-02-20T22:32:55Z

Llarpiwhal:

Scopolamine, also known as hyoscine and devil's breath, is a deliriant tropane alkaloid that occurs naturally in various nightshades including Belladonna and Datura. It has been used for centuries as a poison in some cultures, and is used as a motion sickness medication. Scopolamine is toxic at recreational doses. It appears to impair memory and learning ability.

=== Dosage ===
Note: DO NOT take scopolamine in its plant form, for potency can vary drastically.

Recreational doses appear to range between .5mg-1mg (Don't go above 1mg unless you are under medical supervision)

Another form of scopolamine is smoked Buscopan tablets, which contain butylscopolamine, a form of scopolamine that doesn't cross the BBB, but which is converted to scopolamine when burned via pyrolysis. A dose via this method appears to be 2-3 tablets based on Erowid experience reports.

=== Duration ===
{|
|-
| Onset || 20-120 minutes
| Total || 3-24+ hours
|}

=== Effects ===
===== Positive =====
* Euphoria

===== Neutral =====
*Pupil dilation
*Blurred vision
*Sedation

===== Negative =====
*Delirium
*Tachycardia
*Irregular heartbeat
*Nausea
*Urinary retention
*Abnormal breathing
*Dry mouth
*Anxiety/Panic
*Confusion
*Memory loss
*Skin reddening
*Increased body temperature

===== After Effects =====
People often report not being able to read fine text for the next day or so.

=== Harm Reduction ===
Physostigmine can be used to treat the effects of scopolamine.
Do not mix Scopolamine with other anticholinergics, alcohol, zolpidem, or stimulants.
Due to the delirium caused by scopolamine, one should not combine scopolamine with other hallucinogens.
Having a trip sitter present is extra important with deliriants, for the user is unable to reliably discern what is real.

=== Pharmacology ===
Scopolamine is an antimuscarinic at the m1 receptor

=== Links ===
*[https://erowid.org/chemicals/scopolamine/scopolamine.shtml Erowid]
*[https://psychonautwiki.org/wiki/Datura#Pharmacology PsychonautWiki]
*[https://en.wikipedia.org/wiki/Hyoscine#Mechanism_of_action Wikipedia]

[[Category:Drugs]]
[[Category:Deliriant]]

Scopolamine

2018-02-20T00:34:26Z

Llarpiwhal:

Scopolamine, also known as hyoscine and devil's breath, is a deliriant tropane alkaloid that occurs naturally in various nightshades including Belladonna and Datura. It has been used for centuries as a poison in some cultures, and is used as a motion sickness medication. Scopolamine is toxic at recreational doses. It appears to impair memory and learning ability.

=== Dosage ===
Note: DO NOT take scopolamine in its plant form, for potency can vary drastically.

Recreational doses appear to range between .5mg-1mg (Don't go above 1mg unless you are under medical supervision)

Another form of scopolamine is smoked Buscopan tablets, which contain butylscopolamine, a form of scopolamine that doesn't cross the BBB, but which is converted to scopolamine when burned via pyrolysis. A dose via this method appears to be 2-3 tablets based on Erowid experience reports.

=== Duration ===
{|
|-
| Onset || 20-120 minutes
| Total || 3-24+ hours
|}

=== Effects ===
===== Positive =====
* Euphoria

===== Neutral =====
*Pupil dilation
*Blurred vision
*Sedation

===== Negative =====
*Delirium
*Tachycardia
*Irregular heartbeat
*Nausea
*Urinary retention
*Abnormal breathing
*Dry mouth
*Anxiety/Panic
*Confusion
*Memory loss
*Skin reddening
*Increased body temperature

===== After Effects =====
People often report not being able to red fine text for the next day or so.

=== Harm Reduction ===
Physostigmine can be used to treat the effects of scopolamine.
Do not mix Scopolamine with other anticholinergics, alcohol, zolpidem, or stimulants.
Due to the delirium caused by scopolamine, one should not combine scopolamine with other hallucinogens.
Having a trip sitter present is extra important with deliriants, for the user is unable to reliably discern what is real.

=== Pharmacology ===
Scopolamine is an antimuscarinic at the m1 receptor

=== Links ===
*[https://erowid.org/chemicals/scopolamine/scopolamine.shtml Erowid]
*[https://psychonautwiki.org/wiki/Datura#Pharmacology PsychonautWiki]
*[https://en.wikipedia.org/wiki/Hyoscine#Mechanism_of_action Wikipedia]

[[Category:Drugs]]
[[Category:Deliriant]]

Scopolamine

2018-02-20T00:02:01Z

Llarpiwhal: I made this page from the ground up. Before, this page was one line of text that just said scopolamine was the main component in Datura and to avoid it

Scopolamine, also known as hyoscine and devil's breath, is a deliriant tropane alkaloid that occurs naturally in various nightshades including Belladonna and Datura. It has been used for centuries as a poison in some cultures, and is used as a motion sickness medication. Scopolamine is toxic at recreational doses.

=== Dosage ===
Note: DO NOT take scopolamine in its plant form, for potency can vary drastically.

Recreational doses appear to range between .5mg-1mg

Another form of scopolamine is smoked Buscopan tablets, which contain butylscopolamine, a form of scopolamine that doesn't cross the BBB, but which is converted to scopolamine when burned via pyrolysis. A dose via this method appears to be 2-3 tablets based on Erowid experience reports.

=== Duration ===
{|
|-
| Onset || 20-120 minutes
| Total || 3-24+ hours
|}

=== Effects ===
===== Positive =====
* Euphoria

===== Neutral =====
*Pupil dilation
*Blurred vision
*Sedation

===== Negative =====
*Delirium
*Tachycardia
*Irregular heartbeat
*Nausea
*Urinary retention
*Abnormal breathing
*Dry mouth
*Anxiety/Panic
*Confusion
*Memory loss
*Skin reddening
*Increased body temperature

===== After Effects =====
People often report not being able to red fine text for the next day or so.

=== Harm Reduction ===
Physostigmine can be used to treat the effects of scopolamine.
Do not mix Scopolamine with other anticholinergics, alcohol, zolpidem, or stimulants.
Due to the delirium caused by scopolamine, one should not combine scopolamine with other hallucinogens.
Having a trip sitter present is extra important with deliriants, for the user is unable to reliably discern what is real.

=== Pharmacology ===
Scopolamine is an antimuscarinic at the m1 receptor

=== Links ===
*[https://erowid.org/chemicals/scopolamine/scopolamine.shtml Erowid]
*[https://psychonautwiki.org/wiki/Datura#Pharmacology PsychonautWiki]
*[https://en.wikipedia.org/wiki/Hyoscine#Mechanism_of_action Wikipedia]

[[Category:Drugs]]
[[Category:Deliriant]]

User:Llarpiwhal

2018-02-19T03:35:48Z

Llarpiwhal: create user page

Main Page

2018-02-19T03:24:57Z

Llarpiwhal: /* Drug Knowledge */

{{DISPLAYTITLE:Welcome to TripSit Wiki!<span style="display: none"></span>}}
<table style="display:block;" cellpadding=0>
<tr>
<td valign=top width=30% bgcolor=#f1f1f1>

=== Drug Knowledge ===
*'''List of [[:Category:Drugs|Psychoactive Substances]]'''
*Main pages for drug classes:
**[[Hallucinogens]]
***[[Psychedelics]]
***[[Dissociatives]]
***[[Deliriants]]
**[[Stimulants]]
**[[Depressants]]
***[[Opioids]]
***[[Benzodiazepines]]
**[[Antidepressants]]
**[[:Category:Ethnobotanical|Ethnobotanicals]]
**[[Research Chemicals]]

* [[Drug combinations]]
* [http://drugs.tripsit.me/ Factsheets]
* [[Glossary]]

=== [[Guides]] ===

* [[Addiction]]
* [[Overdose]]
* [[Panic Attacks]]
* [[How To Deal With A Bad Trip]]
* [[Common Misconceptions About Psychedelics]]
* [[Quick Guide to Plugging]]
* [[Quick Guide to Stimulant Comedowns]]
* [[Quick Guide to Volumetric Dosing]]
* [[Cold Water Extraction]]

=== Tripsitting ===
* [[How_To_Tripsit_Online|How to Tripsit online]]
* [[How_To_Tripsit_In_Real_Life|How to Tripsit in real life]]
* [[List_Of_Trip_Toys|List of trip toys]]

=== Harm Reduction Supplies & Testing ===
* [[Scales]]
* [[Test Kits]]
* [[Sources for Laboratory Analysis]]

</td>
<td valign=top width=30% bgcolor=#f1f1f1>
=== [[:Category:Common Drugs|Common Drugs]] ===

* '''[[:Category:Psychedelic|Psychedelics]]'''
** [[2C-X|2C-X series]]
** [[AMT|αMT]]
** [[Cannabis]]
** [[DMT]]
** [[DOx|DOx series]]
** [[LSA]]
** [[LSD]]
** [[Mescaline]]
** [[Mushrooms]]
** [[NBOMes|NBOMe series]]

* '''[[:Category:Dissociative|Dissociatives]]'''
** [[3-MeO-PCP]]
** [[DXM]]
** [[Diphenidine]]
** [[Ketamine]]
** [[MXE]]
** [[Nitrous Oxide]]
** [[PCP]]
** [[Salvia]]

* '''[[:Category:Stimulant|Stimulants]]'''
** [[Adderall]]
** [[Amphetamine]]
** [[Cocaine]]
** [[MDA]]
** [[MDMA]]
** [[Mephedrone]]
** [[Methamphetamine]]
** [[Methylphenidate]]

* '''[[:Category:Depressant|Depressants]]'''
** [[Alcohol]]
** [[Etizolam]]
** [[GHB]]
** [[Kava]]
** [[Zolpidem]]

* '''[[:Category:Opioid|Opioids]]'''
** [[Buprenorphine]]
** [[Codeine]]
** [[Heroin]]
** [[Hydrocodone]]
** [[Kratom]]
** [[Morphine]]
** [[Oxycodone]]
** [[Tramadol]]
</td>

<td valign=top width=20%>
=== '''Important Pages''' ===
* '''[[TripSit Rules]]'''
* [[Network Terms of Service]]
* [[List of staff and their roles]]
* [[TripSit's Plans]]
* [[How to help TripSit]]

=== IRC ===
* [[IRC_User_Guide|'''New user guide''']]
* [http://tripsit.me/tripsitapp/ Tripsit's portable IRC distribution]
* [[Channels]]
** [http://chat.tripsit.me/?nick=Social?#tripsit #tripsit]
** [http://chat.tripsit.me/?nick=Social?#lounge #lounge]
** [http://chat.tripsit.me/?nick=Social?#drugs #drugs]
* [[How_to_connect_through_Tor|How to Connect through Tor]]
* [[How_to_Connect_using_IRCCloud|How to Connect using IRCCloud]]
* [[List of IRC bot commands]]
* Moderation [[Commands reference]]

=== TripRadio ===
* [http://radio.tripsit.me Listen Now]

* [[Radio|General info]]
* [[DJ Application|We need DJs!]]
* [[How to DJ|How to setup DJ software]]
</td>

</tr>
</table>

[[About|About Tripsit wiki]]

TripSit wiki currently has [[Special:Statistics|{{NUMBEROFPAGES}} pages]].

View a [[Special:AllPages|list of all pages]].