General Information

Classification: Opiate/Downer/Sedative/Painkiller/SNRISerotonin–Norepinephrine Reuptake Inhibitor/Reuptake inhibitor of serotoninA monoamine neurotransmitter, biochemically derived from tryptophan, that is primarily found in the gastrointestinal (GI) tract, platelets, and central nervous system (CNS) of humans and animals. It is a well-known contributor to feelings of well-being. and of norepinephrine

History

Dosage

  • 150mg-200mg (No tolerance)
  • 200mg-250mg (Medium-High tolerance)
  • 300mg-400mg (Very High tolerance, WARNING: Seizure threshold is DANGEROUSLY lowered at this point)
  • 400mg+ (Extremely High tolerance, potentially fatal for new users WARNING: Seizure threshold is DANGEROUSLY lowered at this point)


Onset:

  • Oral: 1-2 hours

Peak Benefit:

  • Oral: 3-4 hours

Duration

  • Long onset, slowly building to a peak by hour 4 with maximum blood concnetration acheived near hour 4.5
  • Half-life: 5.5-7 hours

Potentiators/avoiders:

  • Alcohol
  • Other CNSCentral Nervous System depressants

The following products may react negatively with oxycodone and may cause overdose if mixed together.

  • Alcohol
  • Diphenhydramine

WARNING

  • Tramadol effects serotoninA monoamine neurotransmitter, biochemically derived from tryptophan, that is primarily found in the gastrointestinal (GI) tract, platelets, and central nervous system (CNS) of humans and animals. It is a well-known contributor to feelings of well-being. levels in the brain. For this reason it is reccomended to taper on, and taper off use. This drug has very little potential for abuse, due to it being a WEAK opiate agonistA substance that initiates a physiological response when combined with a receptor..

Effects

Do not drive or operate machinery while under the influence of tramadol.


Positive

  • Euphoria
  • Painfree
  • Overall feeling of contentedness

Neutral

  • Itching

Negative

Some users may experience

  • Nausea
  • Constipation
  • CNSCentral Nervous System depression
  • Drowsiness
  • hot/cold flashes
  • Dizziness
  • Vomiting

In high doses, overdoses, or in patients not tolerant to opiates, tramadol can cause shallow breathing, bradycardia, cold-clammy skin, apnea, hypotension, miosis, circulatory collapse, respiratory arrest, and death.

Harm Reduction

Don't take any more tramadol than you are prescribed.

Do not consume alcohol or other drugs while under the influence of Tramadol

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