Skullcap is a component of smoking blends with
alleged psychoactive effects that are offered as a
marijuana substitute (see Cannabis indica). The
herbage formerly was used as a sedative and nerve
tonic and was even prescribed for the treatment of
epilepsy, neuralgia, and sleeplessness. The plant
contains the flavonoid scutellarin, which has
sedative and antispasmodic effects (Foster and Duke 1990, 186*). A species described under the
name Scutellaria arvense is reputed to have
psychoactive or hallucinogenic effects (Schultes
and Hofmann 1980, 367*).

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