Scopolamine
Scopolamine, also known as hyoscine and devil's breath, is a deliriant tropane alkaloid that occurs naturally in various nightshades including Belladonna and Datura. It has been used for centuries as a poison in some cultures, and is used as a motion sickness medication. Scopolamine is toxic at recreational doses.
Dosage
Note: DO NOT take scopolamine in its plant form, for potency can vary drastically.
Recreational doses appear to range between .5mg-1mg
Another form of scopolamine is smoked Buscopan tablets, which contain butylscopolamine, a form of scopolamine that doesn't cross the BBB, but which is converted to scopolamine when burned via pyrolysis. A dose via this method appears to be 2-3 tablets based on Erowid experience reports.
Duration
| Onset | 20-120 minutes | Total | 3-24+ hours |
Effects
Positive
- Euphoria
Neutral
- Pupil dilation
- Blurred vision
- Sedation
Negative
- Delirium
- Tachycardia
- Irregular heartbeat
- Nausea
- Urinary retention
- Abnormal breathing
- Dry mouth
- Anxiety/Panic
- Confusion
- Memory loss
- Skin reddening
- Increased body temperature
After Effects
People often report not being able to red fine text for the next day or so.
Harm Reduction
Physostigmine can be used to treat the effects of scopolamine. Do not mix Scopolamine with other anticholinergics, alcohol, zolpidem, or stimulants. Due to the delirium caused by scopolamine, one should not combine scopolamine with other hallucinogens. Having a trip sitter present is extra important with deliriants, for the user is unable to reliably discern what is real.
Pharmacology
Scopolamine is an antimuscarinic at the m1 receptor