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Volumetric dosing is a relatively easy way to accurately dose substances in the sub-milligram range. It involves dissolving a known quantity of a substance in a known quantity of water, from there it's very easy to find the concentration of the substance on a milliliter basis.
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#REDIRECT [[Quick Guide to Volumetric Dosing]]
 
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==Why?==
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Some substances, such as the NBOMe series, are active at sub-milligram doses. These types of chemicals require extreme precision that can't be achieved with consumer grade scales. Volumetric dosing is the only way to dose something like that in a safe and reliable manner.
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==How?==
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# Research what your substance can be dissolved in, and at what concentrations. Some drugs (Such as alprazolam powder) are not dissolved readily in water, and instead need a strong spirit such as PGP or everclear. Sometimes, it is necessary to use a stronger solute when a higher concentration is desired.
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# Take the substance you wish to dissolve, and weigh it with an accurate milligram scale. (Generally you measure out a substantial amount more than you intend on dosing, to increase the margin of error)
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# Once you have a known quantity, you need to decide what concentration you want it. For example, if I have 100mg of 25i-NBOMe in powder, and I want 500µg in every milliliter of solute (A concentration of 500µg/mL) I would need 200mL of solute.
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: The concentration can be calculated with the following formula
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:: quantity of substance / amount of solute = concentration.
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::: Ex. 100mg/200mL=500µg per mL
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:::'''Remember: The lower the concentration, the easier and safer it is to dose! Ensure your margin for error is as high as necessary.'''
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Latest revision as of 15:51, 21 July 2014

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