Pregnancy categories for commonly used drugs or special risks


How the categories work:

In regards to threats to the health and viability of a fetus, there are 6 categories that the FDA (Food and Drug Administration) use to categorize the safety of a drug is during pregnancy. The main 5 categories are categories A B C D and X ordered from safest (A) to least safe (X). The last other category is N which means there is no statement from the FDA on how safe it is. In general, category A means that human and animal trials have proven to do no harm to the fetus (generally in the first trimester). Category B means that animal studies show no risk to the fetus, but there is not enough data in regards to human trials to determine its safety. Category C is when animal trials show risk to the fetus but there is not enough data from human consumption to make a further statement. Categories D and X somewhat overlap eachother: Both mean that animal and human trials show risk to the fetus however category D drugs may in rare occasions be used despite the risk if there is sufficient benefit (usually in terms of life or death situations involving the pregnant mother),

https://www.drugs.com/pregnancy-categories.html

[Everything needs to be re-ordered to be alphabetical when possible and possible made into a table]


For those who are pregnant or plan on becoming pregnant, abusing recreation drugs is extremely discouraged. Regardless however, some may decide to abuse drugs anyway and so here is some basic information on pregnancy risks and categories of commonly abused drugs

DISCLAIMER: We are NOT medical professionals of any sort. What you choose to do with this information is your decision and we hold no responsibility for it. This page is simply a compilation of peer reviewed and cited information in regards to pregnancy risks. We hope that if you are in fact pregnant that you partake in absolutely NO drug use whatsoever, however this page is for those of you who will regardless and serves to promote harm reduction. Remember, the safest thing you can do while pregnant is to avoid drugs completely.

[Need to have both brand and generic names, and place in same order. preferrably Generic name: Brand names]

[For now place a source for any information added directly below the information (create a seperate line below the info for the source). Absolutely no information without a source will be acceptable and any information without a source will be deleted. All sources must come from reputable sites and preferrably be peer reviewed. For now simply link to the site page url you used until all citations can be made into the proper format later on]


Alcohol


Stimulants

Amphetamine sulfate (Adderall): Pregnancy category C according to the FDA. Evidence has shown usage during pregnancy can cause premature birth, low birthweight, and withdrawal syndrome in the baby. This occurs more often in abuse of adderall. Recommendation is to consult with a physician if you are pregnant.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/011522s040lbl.pdf

https://www.drugs.com/adderall.html

Caffeine

Cocaine

Crack (is it freebase cocaine? look into this)

Dextroamphetamine (Dexedrine): Pregnancy category C according to the FDA. Animal trials indicate teratogenic effects meaning that it affects the genes of the fetus causing congenital defects. One reported human case supports this theory

https://www.drugs.com/pregnancy/dextroamphetamine.html

http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/017078s042lbl.pdf

Evekeo: Pregnancy category C according to the manufacturers site. dextroamphetamine (50% of the ingredients in evekeo) caused congenital defects in mice.

https://www.evekeo.com/assets/evekeo-pi.pdf

Focalin

MDMA

Methamphetamine

Methylphenidate (Ritalin, Concerta): Pregnancy category C according to the FDA. High doses administered to rabbits in animal studies resulted in fetuses having congenital malformations (spina bifida mainly which is an incomplete development of the spine).

http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/010187s069,018029s040,021284s011lbl.pdf

Nicotine

Vyvanse


Opioids

Fentanyl

Heroin

Hydromorphone

Ketobemidone

Morphine

Norcos

Oxycodone

Oxymorphone

Vicodin

U4700 (spell check)


Benzodiazepines

In general the FDA has found that benzodiazepines as a class increase the risk for congenital malformations for the fetus when taken by a pregnant mother and should only be taken when the benefits absolutely outweigh the risks

Alprazolam (Xanax): Pregnancy category D according to the FDA. Potential to cause congenital defects with the fetus if used during pregnancy.

http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018276s044,021434s006lbl.pdf

Bromazepam

Brotizolam

Chlordazepoxide

Clobazam

Clonazepam

Clorazepate

Diazepam (Valium): Pregnancy category D according to the FDA. Potential to cause congenital defects proven through animal studies.

http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/013263s083lbl.pdf

Diclazepam

Estazolam

Etizolam

Flubromazepam

Flubromazolam

Flunitrazepam

Flutoprazepam

Flurazepam

Halazepam

Ketazolam

Loprazolam

Lorazepam (Ativan): Pregnancy category D according to the FDA. Studies in animals show potential for congenital defects. Newborns upon delivery from mothers who used Ativan late into their trimesters were seen to have respiratory depression or stopped breathing completely.

http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/017794s034s035lbl.pdf

http://www.accessdata.fda.gov/drugsatfda_docs/label/2006/018140s028lbl.pdf

Lormetazepam

Medazepam

Midazolam (Versed): Pregnancy category D according to the FDA. Studies show increased chance of congenital malformations

https://www.drugs.com/pregnancy/midazolam.html

http://www.fda.gov/ohrms/dockets/dailys/01/Mar01/032101/cp00001_exhibit_02.pdf

Nitrazepam

Nordazepam

Oxazepam

Phenazepam

Prazepam

Pyrazolam

Quazepam

Temazopam

Triazolam


SSRIs

Citalopram

Escitalopram

Fluoxetine

Paroxetine

Sertraline


SNRIs


SARIs


NDRIs


MAOIs


TCAs


TeCAs


NMDAN-methyl-D-aspartate receptor. NMDA antagonists are often dissociatives. antagonists


Other antidepressants


Deliriants

DPH

Datura

Scopolamine

Tobacco

Top Contributors