Pregnancy categories for commonly used drugs or special risks
How the categories work:
In regards to threats to the health and viability of a fetus, there are 6 categories that the FDA (Food and Drug Administration) use to categorize the safety of a drug is during pregnancy. The main 5 categories are categories A B C D and X ordered from safest (A) to least safe (X). The last other category is N which means there is no statement from the FDA on how safe it is. In general, category A means that human and animal trials have proven to do no harm to the fetus (generally in the first trimester). Category B means that animal studies show no risk to the fetus, but there is not enough data in regards to human trials to determine its safety. Category C is when animal trials show risk to the fetus but there is not enough data from human consumption to make a further statement. Categories D and X somewhat overlap eachother: Both mean that animal and human trials show risk to the fetus however category D drugs may in rare occasions be used despite the risk if there is sufficient benefit (usually in terms of life or death situations involving the pregnant mother),
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For those who are pregnant or plan on becoming pregnant, abusing recreation drugs is extremely discouraged. Regardless however, some may decide to abuse drugs anyway and so here is some basic information on pregnancy risks and categories of commonly abused drugs
[Add disclaimer that we are non medical professionals here]
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Amphetamine sulfate (Adderall): Pregnancy category C according to the FDA. Evidence has shown usage during pregnancy can cause premature birth, low birthweight, and withdrawal syndrome in the baby. This occurs more often in abuse of adderall. Recommendation is to consult with a physician if you are pregnant.
Crack (is it freebase cocaine? look into this)
Dextroamphetamine (Dexedrine): Pregnancy category C according to the FDA. Animal trials indicate teratogenic effects meaning that it affects the genes of the fetus causing congenital defects. One reported human case supports this theory
Methylphenidate (Ritalin, Concerta): Pregnancy category C according to the FDA. High doses administered to rabbits in animal studies resulted in fetuses having congenital malformations (spina bifida mainly which is an incomplete development of the spine).
U4700 (spell check)
In general the FDA has found that benzodiazepines as a class increase the risk for congenital malformations for the fetus when taken by a pregnant mother and should only be taken when the benefits absolutely outweigh the risks
Alprazolam (Xanax): Pregnancy category D according to the FDA. Potential to cause congenital defects with the fetus if used during pregnancy.
Diazepam (Valium): Pregnancy category D according to the FDA. Potential to cause congenital defects proven through animal studies.
Lorazepam (Ativan): Pregnancy category D according to the FDA. Studies in animals show potential for congenital defects. Newborns upon delivery from mothers who used Ativan late into their trimesters were seen to have respiratory depression or stopped breathing completely.
Midazolam (Versed): Pregnancy category D according to the FDA. Studies show increased chance of congenital malformations
NMDAN-methyl-D-aspartate receptor. NMDA antagonists are often dissociatives. antagonists