Oxymorphone: Difference between revisions

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Oxymorphone was first developed in Germany in 1914. Then patented in the USA by Enda Pharmaceuticals in 1955. Which was then introduced to the United States in January of 1959, and other countries during the same time. It was designed to have a few amount of side effects than Morphine and Heroin.  
Oxymorphone was first developed in Germany in 1914. Then patented in the USA by Enda Pharmaceuticals in 1955. Which was then introduced to the United States in January of 1959, and other countries during the same time. It was designed to have a few amount of side effects than Morphine and Heroin.  


== Dosage ==  
== Dosage ==
Bioavailability of each route of administration. '''Note: Do not take these dosages as a god send. These are rough estimations off my own experience with it. Be safe and remember you can always take more, but you can never take less.'''


'''Oral''': 10% (Ways you can imporove this include, taking a large meal of fatty foods before taking it, which could raise it as high as 40%) Crushing the pill as finely as possilbe could make it hit stronger, but also make it last shorter.
'''Insufflated''': ~43%
'''Rectal''': ~10% (Comparable to oral administration, and would lower nausea and vomiting)
'''Intravenous''': 98%+ '''(NOTE: Never inject a pill without a micron filter and a clean syringe)'''
'''Oral/Plugged''': Low: 5-7.5mg Common: 10-20mg Heavy: 20mg+
'''Insufflated''': Low: 2-4mg's Common: 5-10mg's Heavy: 10-15mg+
'''Intravenous''': Low 1-2mg’s Common: 2-5mg’s Heavy: 5-10mg+
'''Onset'''
:IR orally: 20-40 minutes.
:ER orally: 60-90 minutes.
:Insufflated: Near instant within 10 minutes.
:Rectal: 15-30 minutes
:Intravenous: Instant.
'''Duration'''
:Oral: 6-12 hours.
:Insufflated: 3-4 hours.
:Plugged: 4-6 hours.
:Intravenous: 2-3 hours.


== Images ==  
== Images ==  

Revision as of 12:02, 4 February 2014

General information

General Description

Oxymorphone is a powerful semi-synthetic opioid analgesic. Is seven times more potent than morphine itself thus having a 0.4mg:10mg Morphine ratio. (Assuming 100% bioavailability with both substances)

Introduction

Oxymorphine is found in three forms that are used in medical practice and what most of us would encounter if using the drug recreationally. Opana IR(Instant release) which is available in 5mg and 10mg tablets. Opana ER(Extended Release) Which is available in 5, 10, 20, 30, and 40mg tablets. (Generic Opana ER comes in 7.5mg and 15mg tablets.) Oxymorphone Ampoules which are very rare, but come as 1mg/ml.

Because Oxymorphone is from the opioid family, users should experience major caution when using this substance for many days in a row, and also avoid mixing any other depressants when in use with them. (Some examples are Alcohol, Benzodiazepines, Barbiturates and/or other opioids)

Oxymorphone before the half of the old formulation it was commonly taken insufflated. Now with the addition of the new ER mechanism, users are either changing to a different substance, or they are using one of the methods used to break that ER mechanism. Which are very tedious and in my opinion not worth it, but you should be able to find a TEK online rather easily.


History

Oxymorphone was first developed in Germany in 1914. Then patented in the USA by Enda Pharmaceuticals in 1955. Which was then introduced to the United States in January of 1959, and other countries during the same time. It was designed to have a few amount of side effects than Morphine and Heroin.

Dosage

Bioavailability of each route of administration. Note: Do not take these dosages as a god send. These are rough estimations off my own experience with it. Be safe and remember you can always take more, but you can never take less.

Oral: 10% (Ways you can imporove this include, taking a large meal of fatty foods before taking it, which could raise it as high as 40%) Crushing the pill as finely as possilbe could make it hit stronger, but also make it last shorter.

Insufflated: ~43%

Rectal: ~10% (Comparable to oral administration, and would lower nausea and vomiting)

Intravenous: 98%+ (NOTE: Never inject a pill without a micron filter and a clean syringe)

Oral/Plugged: Low: 5-7.5mg Common: 10-20mg Heavy: 20mg+

Insufflated: Low: 2-4mg's Common: 5-10mg's Heavy: 10-15mg+

Intravenous: Low 1-2mg’s Common: 2-5mg’s Heavy: 5-10mg+


Onset

IR orally: 20-40 minutes.
ER orally: 60-90 minutes.
Insufflated: Near instant within 10 minutes.
Rectal: 15-30 minutes
Intravenous: Instant.


Duration

Oral: 6-12 hours.
Insufflated: 3-4 hours.
Plugged: 4-6 hours.
Intravenous: 2-3 hours.

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