Methamphetamine: Difference between revisions

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= General Information =
Methamphetamine is a strong physical and mental stimulant available in both prescription and street forms. It is relatively easy to synthesize which has contributed to its widespread use.


== General Information ==
== History ==
Amphetamine, discovered before methamphetamine, was first synthesized in 1887 in Germany by Romanian chemist Lazăr Edeleanu who named it phenylisopropylamine. Shortly after, methamphetamine was synthesized from ephedrine in 1893 by Japanesechemist Nagai Nagayoshi. Three decades later, in 1919, methamphetamine hydrochloride was synthesized by pharmacologist Akira Ogata via reduction of ephedrine using red phosphorus and iodine. During World War II, methamphetamine was used extensively by the Axis forces for its stimulant effects. Obetrol, patented by Obetrol Pharmaceuticals in the 1950s and indicated for treatment of obesity, was one of the first brands of pharmaceutical methamphetamine products. Due to the psychological and stimulant effects of methamphetamine, Obetrol became a popular diet pill in America in the 1950s and 1960s. Eventually, as the addictive properties of the drug became known, governments began to strictly regulate the production and distribution of methamphetamine. For example, during the early 1970s in the United States, methamphetamine became a schedule II controlled substance under the Controlled Substances Act. Currently, methamphetamine is sold under the trade name Desoxyn, trademarked by the Danish pharmaceutical company Lundbeck. As of January 2013, the Desoxyn trademark had been sold to Italian pharmaceutical company Recordati.


Methamphetamine is a strong physical and mental stimulant available in both prescription and street forms. It is relatively easy to synthesize which has contributed to its widespread use.
= Dosage =


=== History ===
== Oral ==
Amphetamine, discovered before methamphetamine, was first synthesized in 1887 in Germany by Romanian chemist Lazăr Edeleanu who named it phenylisopropylamine. Shortly after, methamphetamine was synthesized from ephedrine in 1893 by Japanesechemist Nagai Nagayoshi. Three decades later, in 1919, methamphetamine hydrochloride was synthesized by pharmacologist Akira Ogata via reduction of ephedrine using red phosphorus and iodine. During World War II, methamphetamine was used extensively by the Axis forces for its stimulant effects. Obetrol, patented by Obetrol Pharmaceuticals in the 1950s and indicated for treatment of obesity, was one of the first brands of pharmaceutical methamphetamine products. Due to the psychological and stimulant effects of methamphetamine, Obetrol became a popular diet pill in America in the 1950s and 1960s. Eventually, as the addictive properties of the drug became known, governments began to strictly regulate the production and distribution of methamphetamine. For example, during the early 1970s in the United States, methamphetamine became a schedule II controlled substance under the Controlled Substances Act. Currently, methamphetamine is sold under the trade name Desoxyn, trademarked by the Danish pharmaceutical company Lundbeck. As of January 2013, the Desoxyn trademark had been sold to Italian pharmaceutical company Recordati.


== Dosage ==
Light: 5-15 mg


=== Oral ===
Common: 10-30 mg
Oral: Light 5-15mg


Common 10-30mg
Strong: 20-60 mg


Strong 20-60mg
Heavy: 40-150+ mg


Heavy 40-150mg
== Insufflated ==


===Insufflated===
Light: 5-15 mg
Light 5-15mg


Common 10-40mg
Common: 10-40 mg


Strong: 30-60mg
Strong: 30-60 mg


Heavy: 50mg+
Heavy: 50mg+


===Smoked===
== Smoked ==
Light 5-10mg


Common: 10-20mg
Light: 5-10 mg


Strong 30-60mg
Common: 10-20 mg
 
Strong 30-60 mg


Heavy: 50mg+
Heavy: 50mg+


===Intravenous (IV)===
== Intravenous (IV) ==


Light: 5-10mg
Light: 5-10 mg


Common: 10-40mg
Common: 10-40 mg


Strong 30-60mg
Strong 30-60mg
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Heavy: 50-100mg
Heavy: 50-100mg


== Duration ==
= Duration =
 
== Oral ==


===Oral===
Onset: 20-70 minutes
Onset: 20-70 minutes


Total duration: 3-5 hours
Total: 3-5 hours
 
== Insufflated ==


===Insufflated===
Onset: 5-10 minutes
Onset: 5-10 minutes


Total duration: 2-4 hours
Total: 2-4 hours
 
== Smoked ==


===Smoked===
Onset: 0-2 minutes  
Onset: 0-2 minutes  


Total duration: 1-3 hours
Total: 1-3 hours
 
== Intravenous (IV) ==


===Intravenous (IV)===
Onset: 0-2 minutes
Onset: 0-2 minutes


Total duration: 4-8 hours
Total: 4-8 hours
 


== Effects ==  
= Effects =
===Positive===
== Positive ==


*Increased energy, alertness
*Increased energy, alertness
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*Increased libido
*Increased libido


===Neutral===
== Neutral ==


*Excessive talking
*Excessive talking
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*Dilated pupils
*Dilated pupils


===Negative===
== Negative ==


*Weight loss
*Weight loss
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*Liver damage
*Liver damage


==Links==
= Links=


http://science.howstuffworks.com/meth3.htm
http://science.howstuffworks.com/meth3.htm

Revision as of 15:06, 2 April 2014

General Information

Methamphetamine is a strong physical and mental stimulant available in both prescription and street forms. It is relatively easy to synthesize which has contributed to its widespread use.

History

Amphetamine, discovered before methamphetamine, was first synthesized in 1887 in Germany by Romanian chemist Lazăr Edeleanu who named it phenylisopropylamine. Shortly after, methamphetamine was synthesized from ephedrine in 1893 by Japanesechemist Nagai Nagayoshi. Three decades later, in 1919, methamphetamine hydrochloride was synthesized by pharmacologist Akira Ogata via reduction of ephedrine using red phosphorus and iodine. During World War II, methamphetamine was used extensively by the Axis forces for its stimulant effects. Obetrol, patented by Obetrol Pharmaceuticals in the 1950s and indicated for treatment of obesity, was one of the first brands of pharmaceutical methamphetamine products. Due to the psychological and stimulant effects of methamphetamine, Obetrol became a popular diet pill in America in the 1950s and 1960s. Eventually, as the addictive properties of the drug became known, governments began to strictly regulate the production and distribution of methamphetamine. For example, during the early 1970s in the United States, methamphetamine became a schedule II controlled substance under the Controlled Substances Act. Currently, methamphetamine is sold under the trade name Desoxyn, trademarked by the Danish pharmaceutical company Lundbeck. As of January 2013, the Desoxyn trademark had been sold to Italian pharmaceutical company Recordati.

Dosage

Oral

Light: 5-15 mg

Common: 10-30 mg

Strong: 20-60 mg

Heavy: 40-150+ mg

Insufflated

Light: 5-15 mg

Common: 10-40 mg

Strong: 30-60 mg

Heavy: 50mg+

Smoked

Light: 5-10 mg

Common: 10-20 mg

Strong 30-60 mg

Heavy: 50mg+

Intravenous (IV)

Light: 5-10 mg

Common: 10-40 mg

Strong 30-60mg

Heavy: 50-100mg

Duration

Oral

Onset: 20-70 minutes

Total: 3-5 hours

Insufflated

Onset: 5-10 minutes

Total: 2-4 hours

Smoked

Onset: 0-2 minutes

Total: 1-3 hours

Intravenous (IV)

Onset: 0-2 minutes

Total: 4-8 hours

Effects

Positive

  • Increased energy, alertness
  • Sleep suppression
  • Increased sociability
  • Mood elevation
  • Increased libido

Neutral

  • Excessive talking
  • Decreased appetite
  • Sweating
  • Dilated pupils

Negative

  • Weight loss
  • Disturbed sleep patterns, Insomnia
  • Bruxia
  • Drying of oral mucosa
  • Loss of appetite
  • Visual and auditory hallucinations
  • Itchiness
  • Aggressiveness
  • Moodiness, Irritability, Anxiety
  • Increased heart rate, Irregular heart rhythm
  • Excessive sweating, Dehydration
  • Fatal kidney disorder
  • Possible brain damage
  • Liver damage

Links

http://science.howstuffworks.com/meth3.htm

http://en.wikipedia.org/wiki/Methamphetamine