Heroin (Diacetylmorphine, Morphine Diacetate and also Diamorphine) was first synthesized in 1874 by English chemist C.R. Wright. But its commercial value was first recognized in 1897 by Heinrich Dreser and Felix Hoffman at the Bayer pharmaceutical laboratory - the same researchers who invented aspirin, which is is made by a similar process. Heroin was intended to be a less-addictive substitute for other common opiates.
In the late nineteenth and early twentieth centuries, heroin was common in over-the-counter medicines, but it was made illegal in the United States in 1924 through the Heroin Act. In the second half of the twentieth century, heroin was widely stigmatized as the quintessential illicit drug, as images of urban heroin addicts were propagated by media reports.
1: Morphine Freebase or Morphine HCl.
2: Heroin Acetate or Heroin Freebase.
3: Similar to #4 Heroin but specifically altered at the point of manufacture to make it conducive for smoking. The technical definition is a 60:40 mix, with 60 representing Heroin HCl and 40 representing Caffeine HCl.
4: Heroin HCl, which is a white or grey-ish substance that is easily dissolved and injected.
Black Tar Heroin. In a sense does not fall under the above number, as it uses a completely different method from Opium to Heroin. Contains 6-MAM and 3-MAM (which binds relatively weak to the μ-Opioid receptors).
Note: Purity varies wildly, and with such the dose does also.
|Common (no tolerance)||5-15mg|
|Strong (no tolerance)||10-20mg|
|Common (with tolerance)||20-30mg|
|Strong (with tolerance)||30-50mg|
When injected intravenously, smoked, or insufflated, heroin produces a wash of euphoria followed by a period of sedation lasting for 2-4 hours. Intramuscular and subcutaneous injection typically lack the initial wave of intense euphoria, and cause feelings of sedation lasting three to five hours.
A common misconception is that Grapefruit juice potentiates Morphine and/or Heroin. It does not.
Any first generation anti-histamines.
Hello fellow & former opiate/heroin addicts. I have some very important information that may save your life one day.
There's a good chance you've heard it before, but cannot emphasize how strong its so important to know the following critical information: