General Information

Classification: Depressant

GHB (Gamma-Hydroxybutyric Acid) is a CNSCentral Nervous System depressant used as intoxicant.


GHB was synthesized and introduced into medicine in 1960 and in 1963 discovered as a naturally occurring chemical in the human brain.



Duration: 1-3 hours

Low dose: 0.5-1.5g

Medium (typical) dose: 1-2.5g

High dose: 2-4g

GBL dose: 1ml GBL is equal to 1.6g GHB



  • Relaxation
  • Increased sociability
  • Positive mood changes
  • Euphoria
  • Empatogenic
  • Enhanced sensuality


  • Dizziness


  • Nausea
  • Restlessness
  • Unconsciousness
  • Amnesia

After effects

  • Hangover (usually only occurs from high doses)
  • Sleepiness
  • Drowsiness

Harm Reduction

  • Avoid driving and operating heavy machinery
  • Don't mix it with Alcohol, or only very carefully
  • Recommended time (pauses) between using the substance:
    • 2-3 times a week should be the maximum
  • Addiction potential?
    • High
  • Risk of death?
    • Low

Chemistry and Pharmacology


Production of GHB consists simply of mixing "lactone" (short for gamma butyrlactone) and lye (sodium hydroxide) in the proper amounts. It can also be converted from GBL.

Legal status

GHB is illegal in most parts of the world, GBL is legal in parts of Europe.

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