(Usage)
 
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[[File:Caff.jpg|thumb|500px|Brewed coffee, raw coffee beans and caffeine powder]]
 
[[File:Caff.jpg|thumb|500px|Brewed coffee, raw coffee beans and caffeine powder]]
  
Caffeine is a naturally occurring stimulant, which is unique from most other psychoactive drugs in that it is almost ubiquitously legal and in heavy use worldwide. Ordinary use of the caffeine has a low risk of causing health problems, though many modern cultures engage in a 'caffeine culture' which involves heavy regular use and arguable dependence on the drug.
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'''Caffeine''' is a naturally occurring stimulant, which is unique from most other psychoactive drugs in that it is almost ubiquitously legal and in heavy use worldwide. Ordinary use of the caffeine has a low risk of causing health problems, though many modern cultures engage in a 'caffeine culture' which involves heavy regular use and arguable dependence on the drug.
  
= History =
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== History ==
  
 
Caffeine has been used by humans for thousands of years recreationally. The first documented use of caffeine was in China during 3000 BCE in the form of tea.
 
Caffeine has been used by humans for thousands of years recreationally. The first documented use of caffeine was in China during 3000 BCE in the form of tea.
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Caffeine as a distinct chemical was first isolated in 1819 in Germany, later being independently isolated in 1821 by French and Swedish scientists both. However, it wasn't until 1895 caffeine was first synthesised.
 
Caffeine as a distinct chemical was first isolated in 1819 in Germany, later being independently isolated in 1821 by French and Swedish scientists both. However, it wasn't until 1895 caffeine was first synthesised.
  
= Usage =
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== Usage ==
  
 
The most common consumption method is in a brewed drink (such as tea or [[coffee]]) or in a carbonated beverage, such as soda. Caffeine is also found in several foods, namely chocolate, and can be eaten in capsule or pill form. It can also be bought as a powder, usually in bulk.
 
The most common consumption method is in a brewed drink (such as tea or [[coffee]]) or in a carbonated beverage, such as soda. Caffeine is also found in several foods, namely chocolate, and can be eaten in capsule or pill form. It can also be bought as a powder, usually in bulk.
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It is most commonly used for its properties of mental and physical stimulation, being consumed throughout the day increase concentration and wakefulness. Along with personal use, it is in common use at workplaces throughout the world. There is also a huge industry in shops which exist with the express purpose of selling caffeinated beverages.
 
It is most commonly used for its properties of mental and physical stimulation, being consumed throughout the day increase concentration and wakefulness. Along with personal use, it is in common use at workplaces throughout the world. There is also a huge industry in shops which exist with the express purpose of selling caffeinated beverages.
  
= Dosage =
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== Dosage ==
  
 
The average cup of coffee contains between 90 and 200mg of caffeine. A coca-cola contains on average between 25 and 35mg of caffeine. A cup of black tea averages 14 to 70mg of caffeine. Note: While it's difficult to state specific values for brewed drinks due to the variety of preparation methods, these are the most commonly found values.
 
The average cup of coffee contains between 90 and 200mg of caffeine. A coca-cola contains on average between 25 and 35mg of caffeine. A cup of black tea averages 14 to 70mg of caffeine. Note: While it's difficult to state specific values for brewed drinks due to the variety of preparation methods, these are the most commonly found values.
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= Duration =
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== Duration ==
  
 
Note: Duration can be significantly longer with higher doses.
 
Note: Duration can be significantly longer with higher doses.
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= Effects =
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== Effects ==
  
 
In higher doses, caffeine can cause panicked thinking, racing thoughts, and an uncomfortable bodyload. With ordinary use, people tend to experience little to no after-effects from caffeine alone.
 
In higher doses, caffeine can cause panicked thinking, racing thoughts, and an uncomfortable bodyload. With ordinary use, people tend to experience little to no after-effects from caffeine alone.
  
== Positive ==
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=== Positive ===
  
 
* Stimulation
 
* Stimulation
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* Increased focus
 
* Increased focus
  
== Neutral ==
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=== Neutral ===
  
 
* Basal metabolic rate increase
 
* Basal metabolic rate increase
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* Diuretic effects
 
* Diuretic effects
  
== Negative ==
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=== Negative ===
  
 
* Anxiety
 
* Anxiety
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* Feelings of discomfort
 
* Feelings of discomfort
  
== After effects ==
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=== After effects ===
  
 
* Tiredness (crash)
 
* Tiredness (crash)
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* Irritability
 
* Irritability
  
= Harm Reduction =
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== Harm Reduction ==
  
 
See also information under [[Stimulants]].
 
See also information under [[Stimulants]].
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* Binging on caffeine may cause symptoms of a more general stimulant comedown. See [[Quick Guide to Stimulant Comedowns]] for more.
 
* Binging on caffeine may cause symptoms of a more general stimulant comedown. See [[Quick Guide to Stimulant Comedowns]] for more.
  
==Interactions==
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=== Interactions ===
  
 
Ordinary amounts of caffeine are usually relatively safe in combination with most drugs, however many users find the combination of caffeine with other drugs that stimulate the CNS to be quite uncomfortable.
 
Ordinary amounts of caffeine are usually relatively safe in combination with most drugs, however many users find the combination of caffeine with other drugs that stimulate the CNS to be quite uncomfortable.
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See the [[Drug combinations]] chart for more information.
 
See the [[Drug combinations]] chart for more information.
  
= Chemistry and Pharmacology =
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== Chemistry and Pharmacology ==
  
 
Caffeine is part of the class of substances called "Xanthines"
 
Caffeine is part of the class of substances called "Xanthines"
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Since Caffeine is both lipid and water soluble it crosses the blood brain barrier with ease.
 
Since Caffeine is both lipid and water soluble it crosses the blood brain barrier with ease.
  
== LD50 ==
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=== LD50 ===
  
 
190 milligrams per kilogram
 
190 milligrams per kilogram
  
= Legal status =
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== Legal status ==
  
 
Caffeine is legal in most of the world, though as a psychoactive chemical is usually regulated to some degree; usually occurring in a limit on the amount of caffeine content a product can legally contain.
 
Caffeine is legal in most of the world, though as a psychoactive chemical is usually regulated to some degree; usually occurring in a limit on the amount of caffeine content a product can legally contain.

Latest revision as of 10:09, 10 March 2015

Brewed coffee, raw coffee beans and caffeine powder

Caffeine is a naturally occurring stimulant, which is unique from most other psychoactive drugs in that it is almost ubiquitously legal and in heavy use worldwide. Ordinary use of the caffeine has a low risk of causing health problems, though many modern cultures engage in a 'caffeine culture' which involves heavy regular use and arguable dependence on the drug.

History

Caffeine has been used by humans for thousands of years recreationally. The first documented use of caffeine was in China during 3000 BCE in the form of tea.

Records of coffee use appear somewhat later, around the 15th century in Arabia, from where it spread to Egypt and Africa - later reaching Italy, wider Europe and the rest of the world.

Caffeine as a distinct chemical was first isolated in 1819 in Germany, later being independently isolated in 1821 by French and Swedish scientists both. However, it wasn't until 1895 caffeine was first synthesised.

Usage

The most common consumption method is in a brewed drink (such as tea or coffee) or in a carbonated beverage, such as soda. Caffeine is also found in several foods, namely chocolate, and can be eaten in capsule or pill form. It can also be bought as a powder, usually in bulk.

When imbibed as a brewed drink, the caffeine is usually derived from the natural content existing in the produce of the coffee plant or tea bush.

It is most commonly used for its properties of mental and physical stimulation, being consumed throughout the day increase concentration and wakefulness. Along with personal use, it is in common use at workplaces throughout the world. There is also a huge industry in shops which exist with the express purpose of selling caffeinated beverages.

Dosage

The average cup of coffee contains between 90 and 200mg of caffeine. A coca-cola contains on average between 25 and 35mg of caffeine. A cup of black tea averages 14 to 70mg of caffeine. Note: While it's difficult to state specific values for brewed drinks due to the variety of preparation methods, these are the most commonly found values.

Oral
Threshold 10-20mg
Light 20-150mg
Common 150-250mg
Strong 250-400mg
Heavy 400mg+
Lethal 3 Grams+

Duration

Note: Duration can be significantly longer with higher doses.

Oral
Onset 5-10 minutes
Total 1.5-5 hours

Effects

In higher doses, caffeine can cause panicked thinking, racing thoughts, and an uncomfortable bodyload. With ordinary use, people tend to experience little to no after-effects from caffeine alone.

Positive

  • Stimulation
  • Mild Euphoria
  • Increase in cognitive abilities
  • Increased drive
  • Increased focus

Neutral

  • Basal metabolic rate increase
  • Decreased appetite
  • Increased perspiration
  • Respiratory rate increase
  • Heart rate increase
  • Diuretic effects

Negative

  • Anxiety
  • Jitters
  • Feelings of discomfort

After effects

  • Tiredness (crash)
  • Irritability

Harm Reduction

See also information under Stimulants.

  • Regular use of caffeine can cause dependence and withdrawal, which can last between 3-12 days.

Interactions

Ordinary amounts of caffeine are usually relatively safe in combination with most drugs, however many users find the combination of caffeine with other drugs that stimulate the CNSCentral Nervous System to be quite uncomfortable.

See the Drug combinations chart for more information.

Chemistry and Pharmacology

Caffeine is part of the class of substances called "Xanthines"

Caffeine's mechanism of action is mostly through the adenosine receptor (AntagonistA substance that interferes with or inhibits the physiological action of another. at all of them) Which causes the stimulation.

Since Caffeine is both lipid and water soluble it crosses the blood brain barrier with ease.

LD50The dosage of a substance at which 50% of the exposed subjects does not survive. To estimate the LD50 for humans, tests are conducted on non-human subjects.

190 milligrams per kilogram

Legal status

Caffeine is legal in most of the world, though as a psychoactive chemical is usually regulated to some degree; usually occurring in a limit on the amount of caffeine content a product can legally contain.

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